Publications

Crack nucleation and propagation in microcrystalline-cellulose based granules subject to uniaxial and triaxial load

Jonsson, Henrik; Öhman-Mägi, Caroline; Alderborn, Göran; Isaksson, Per et al.

Part of International Journal of Pharmaceutics, p. 130-137, 2019.

DOI for Crack nucleation and propagation in microcrystalline-cellulose based granules subject to uniaxial and triaxial load

Evaluation of bulk compression using a discrete element procedure calibrated with data from triaxial experiments on single particles

Jonsson, Henrik; Alderborn, Göran; Frenning, Göran

Part of Powder Technology, p. 74-81, 2019.

DOI for Evaluation of bulk compression using a discrete element procedure calibrated with data from triaxial experiments on single particles

Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage

Edueng, Khadijah; Mahlin, Denny; Gråsjö, Johan; Nylander, Olivia et al.

Part of Molecules, 2019.

DOI for Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage Download full text (pdf) of Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage

Long-term physical (in)stability of spray-dried amorphous drugs: relationship with glass-forming ability and physicochemical properties

Edueng, Khadijah; Bergström, Christel; Gråsjö, Johan; Mahlin, Denny

Part of Pharmaceutics, 2019.

DOI for Long-term physical (in)stability of spray-dried amorphous drugs: relationship with glass-forming ability and physicochemical properties

Atypical compaction behaviour of disordered lactose explained by a shift in type of compact fracture pattern

Pazesh, Samaneh; Persson, Ann-Sofie; Alderborn, Göran

Part of International Journal of Pharmaceutics: X, 2019.

DOI for Atypical compaction behaviour of disordered lactose explained by a shift in type of compact fracture pattern Download full text (pdf) of Atypical compaction behaviour of disordered lactose explained by a shift in type of compact fracture pattern

Linking carrier morphology to the powder mechanics of adhesive mixtures for dry powder inhalers via a blend-state model

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Part of International Journal of Pharmaceutics, p. 148-160, 2019.

DOI for Linking carrier morphology to the powder mechanics of adhesive mixtures for dry powder inhalers via a blend-state model Download full text (pdf) of Linking carrier morphology to the powder mechanics of adhesive mixtures for dry powder inhalers via a blend-state model

Milling induced amorphisation and recrystallization of alpha-lactose monohydrate

Tejedor, Maria Badal; Pazesh, Samaneh; Nordgren, Niklas; Schuleit, Michael et al.

Part of International Journal of Pharmaceutics, p. 140-147, 2018.

DOI for Milling induced amorphisation and recrystallization of alpha-lactose monohydrate

A hybrid approach to predict the relationship between tablet tensile strength and compaction pressure using analytical powder compression

Persson, Ann-Sofie; Alderborn, Göran

Part of European journal of pharmaceutics and biopharmaceutics, p. 28-37, 2018.

DOI for A hybrid approach to predict the relationship between tablet tensile strength and compaction pressure using analytical powder compression Download full text (pdf) of A hybrid approach to predict the relationship between tablet tensile strength and compaction pressure using analytical powder compression

Effect of milling on the plastic and the elastic stiffness of lactose particles

Pazesh, Samaneh; Persson, Ann-Sofie; Berggren, Jonas; Alderborn, Göran

Part of European Journal of Pharmaceutical Sciences, p. 138-145, 2018.

DOI for Effect of milling on the plastic and the elastic stiffness of lactose particles Download full text (pdf) of Effect of milling on the plastic and the elastic stiffness of lactose particles

Powder Compression Properties of Paracetamol, Paracetamol Hydrochloride, and Paracetamol Cocrystals and Coformers

Persson, Ann-Sofie; Ahmed, Hamzah; Velaga, Sitaram; Alderborn, Göran

Part of Journal of Pharmaceutical Sciences, p. 1920-1927, 2018.

DOI for Powder Compression Properties of Paracetamol, Paracetamol Hydrochloride, and Paracetamol Cocrystals and Coformers

Determination of interfacial amorphicity in functional powders

Tejedor, Maria Badal; Nordgren, Niklas; Schuleit, Michael; Pazesh, Samaneh et al.

Part of Abstracts of Papers of the American Chemical Society, 2018.

Relationships between surface coverage ratio and powder mechanics of binary adhesive mixtures for dry powder inhalers

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Part of International Journal of Pharmaceutics, p. 143-156, 2018.

DOI for Relationships between surface coverage ratio and powder mechanics of binary adhesive mixtures for dry powder inhalers

Compressibility and tablet forming ability of bimodal granule mixtures: Experiments and DEM simulations

Nordström, Josefina; Alderborn, Göran; Frenning, Göran

Part of International Journal of Pharmaceutics, p. 120-131, 2018.

DOI for Compressibility and tablet forming ability of bimodal granule mixtures: Experiments and DEM simulations

Determination of Interfacial Amorphicity in Functional Powders

Tejedor, Maria Badal; Nordgren, Niklas; Schuleit, Michael; Pazesh, Samaneh et al.

Part of Langmuir, p. 920-926, 2017.

DOI for Determination of Interfacial Amorphicity in Functional Powders

Comminution-amorphisation relationships during ball milling of lactose at different milling conditions

Pazesh, Samaneh; Gråsjö, Johan; Berggren, Jonas; Alderborn, Göran

Part of International Journal of Pharmaceutics, p. 215-227, 2017.

DOI for Comminution-amorphisation relationships during ball milling of lactose at different milling conditions Download full text (pdf) of Comminution-amorphisation relationships during ball milling of lactose at different milling conditions

Confinement of Amorphous Lactose in Pores formed upon Co-Spray-Drying with Nanoparticles

Hellrup, Joel; Mahlin, Denny

Part of Journal of Pharmaceutical Sciences, p. 322-330, 2017.

DOI for Confinement of Amorphous Lactose in Pores formed upon Co-Spray-Drying with Nanoparticles

Production and characterization of aluminium oxide nanoshells on spray dried lactose

Hellrup, Joel; Rooth, Marten; Johansson, Anders; Mahlin, Denny

Part of International Journal of Pharmaceutics, p. 116-122, 2017.

DOI for Production and characterization of aluminium oxide nanoshells on spray dried lactose

The Need for Restructuring the Disordered Science of Amorphous Drug Formulations

Edueng, Khadijah; Mahlin, Denny; Bergström, Christel

Part of Pharmaceutical Research, p. 1754-1772, 2017.

DOI for The Need for Restructuring the Disordered Science of Amorphous Drug Formulations Download full text (pdf) of The Need for Restructuring the Disordered Science of Amorphous Drug Formulations

Powder compression mechanics of spray-dried lactose nanocomposites

Hellrup, Joel; Nordström, Josefina; Mahlin, Denny

Part of International Journal of Pharmaceutics, p. 1-10, 2017.

DOI for Powder compression mechanics of spray-dried lactose nanocomposites

Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways

Edueng, Khadijah; Mahlin, Denny; Larsson, Per; Bergström, Christel

Part of Journal of Controlled Release, p. 193-202, 2017.

DOI for Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways Download full text (pdf) of Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways

Peptide loaded microgels as antimicrobial surface coatings

Nyström, Lina; Nordström, Randi; Frenning, Göran; Saunders, Brian et al.

Part of Abstracts of Papers of the American Chemical Society, 2017.

Mechanical behaviour of ideal elastic-plastic particles subjected to different triaxial loading conditions

Jonsson, Henrik; Gråsjö, Johan; Frenning, Göran

Part of Powder Technology, p. 347-355, 2017.

DOI for Mechanical behaviour of ideal elastic-plastic particles subjected to different triaxial loading conditions Download full text (pdf) of Mechanical behaviour of ideal elastic-plastic particles subjected to different triaxial loading conditions

Computational fluid dynamics (CFD) studies of a miniaturized dissolution system

Frenning, Göran; Ahnfelt, Emelie; Sjögren, Erik; Lennernäs, Hans

Part of International Journal of Pharmaceutics, p. 274-281, 2017.

DOI for Computational fluid dynamics (CFD) studies of a miniaturized dissolution system Download full text (pdf) of Computational fluid dynamics (CFD) studies of a miniaturized dissolution system

Structure and mobility of lactose in lactose/sodium montmorillonite nanocomposites

Hellrup, Joel; Holmboe, Michael; Nartowski, Karol P.; Khimyak, Y.Z et al.

Part of Langmuir, p. 13214-13225, 2016.

DOI for Structure and mobility of lactose in lactose/sodium montmorillonite nanocomposites

Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy

Pazesh, Samaneh; Lazorova, Lucia; Berggren, Jonas; Alderborn, Göran et al.

Part of International Journal of Pharmaceutics, p. 488-504, 2016.

DOI for Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy Download full text (pdf) of Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy

Compression analysis for assessment of pellet plasticity: Identification of reactant pores and comparison between Heckel, Kawakita, and Adams equations

Persson, Ann-Sofie; Nordström, Josefina; Frenning, Göran; Alderborn, Göran

Part of Chemical engineering research & design, p. 183-191, 2016.

DOI for Compression analysis for assessment of pellet plasticity: Identification of reactant pores and comparison between Heckel, Kawakita, and Adams equations

Electrostatic Swelling Transitions in Surface-Bound Microgels

Nyström, Lina; Alvarez-Asencio, Ruben; Frenning, Göran; Saunders, Brian R. et al.

Part of ACS Applied Materials and Interfaces, p. 27129-27139, 2016.

DOI for Electrostatic Swelling Transitions in Surface-Bound Microgels

Investigations of single microcrystalline cellulose-based granules subjected to confined triaxial compression

Jonsson, Henrik; Frenning, Göran

Part of Powder Technology, p. 79-87, 2016.

DOI for Investigations of single microcrystalline cellulose-based granules subjected to confined triaxial compression Download full text (pdf) of Investigations of single microcrystalline cellulose-based granules subjected to confined triaxial compression

Rydberg-Resolved Resonant Inelastic Soft X-Ray Scattering: Dynamics at Core Ionization Thresholds

Rubensson, Jan-Erik; Söderström, Johan; Binggeli, Christian; Gråsjö, Johan et al.

Part of Physical Review Letters, 2015.

DOI for Rydberg-Resolved Resonant Inelastic Soft X-Ray Scattering: Dynamics at Core Ionization Thresholds

Efficient Voronoi volume estimation for DEM simulations of granular materials under confined conditions

Frenning, Göran

Part of MethodsX, p. 79-90, 2015.

DOI for Efficient Voronoi volume estimation for DEM simulations of granular materials under confined conditions Download full text (pdf) of Efficient Voronoi volume estimation for DEM simulations of granular materials under confined conditions

Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability

Alhalaweh, Amjad; Alzghoul, Ahmad; Mahlin, Denny; Bergström, Christel A. S.

Part of International Journal of Pharmaceutics, p. 312-317, 2015.

DOI for Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability Download full text (pdf) of Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability

Inhibition of Recrystallization of Amorphous Lactose in Nanocomposites Formed by Spray-Drying

Hellrup, Joel; Alderborn, Göran; Mahlin, Denny

Part of Journal of Pharmaceutical Sciences, p. 3760-3769, 2015.

DOI for Inhibition of Recrystallization of Amorphous Lactose in Nanocomposites Formed by Spray-Drying

An apparatus for confined triaxial testing of single particles

Jonsson, Henrik; Gråsjö, Johan; Nordström, Josefina; Johansson, Niklas et al.

Part of Powder Technology, p. 121-127, 2015.

DOI for An apparatus for confined triaxial testing of single particles Download full text (pdf) of An apparatus for confined triaxial testing of single particles

The Granule Porosity Controls the Loss of Compactibility for Both Dry- and Wet-Processed Cellulose Granules but at Different Rate

Nordström, Josefina; Alderborn, Göran

Part of Journal of Pharmaceutical Sciences, p. 2029-2039, 2015.

DOI for The Granule Porosity Controls the Loss of Compactibility for Both Dry- and Wet-Processed Cellulose Granules but at Different Rate

Kaolinite: defect states define material properties-a soft x-ray and first principles study of the band gap

Pietzsch, Annette; Nisar, Jawad; Jamstorp, Erik; Gråsjö, Johan et al.

Part of Journal of Electron Spectroscopy and Related Phenomena, p. 11-15, 2015.

DOI for Kaolinite: defect states define material properties-a soft x-ray and first principles study of the band gap

Towards a mechanistic contact model for elastoplastic particles at high relative densities

Frenning, Göran

Part of Finite elements in analysis and design (Print), p. 56-60, 2015.

DOI for Towards a mechanistic contact model for elastoplastic particles at high relative densities Download full text (pdf) of Towards a mechanistic contact model for elastoplastic particles at high relative densities

An experimental evaluation of discrete element simulations of confined powder compression using an extended truncated-sphere model

Persson, Ann-Sofie; Frenning, Göran

Part of Powder Technology, p. 257-264, 2015.

DOI for An experimental evaluation of discrete element simulations of confined powder compression using an extended truncated-sphere model Download full text (pdf) of An experimental evaluation of discrete element simulations of confined powder compression using an extended truncated-sphere model

Chain and Pore-Blocking Effects on Matrix Degradation in Protein-Loaded Microgels

Widenbring, Ronja; Frenning, Göran; Malmsten, Martin

Part of Biomacromolecules, p. 3671-3678, 2014.

DOI for Chain and Pore-Blocking Effects on Matrix Degradation in Protein-Loaded Microgels

Experimental and Computational Prediction of Glass Transition Temperature of Drugs

Alzghoul, Ahmad; Alhalaweh, Amjad; Mahlin, Denny; Bergström, Christel A. S.

Part of JOURNAL OF CHEMICAL INFORMATION AND MODELING, p. 3396-3403, 2014.

DOI for Experimental and Computational Prediction of Glass Transition Temperature of Drugs

The crystallinity of cellulose controls the physical distribution of sorbed water and the capacity to present water for chemical degradation of a solid drug

Höckerfelt, Mina Heidarian; Alderborn, Göran

Part of International Journal of Pharmaceutics, p. 326-333, 2014.

DOI for The crystallinity of cellulose controls the physical distribution of sorbed water and the capacity to present water for chemical degradation of a solid drug

Computational predictions of glass-forming ability and crystallization tendency of drug molecules

Alhalaweh, Amjad; Alzghoul, Ahmad; Kaialy, Waseem; Mahlin, Denny et al.

Part of Molecular Pharmaceutics, p. 3123-3132, 2014.

DOI for Computational predictions of glass-forming ability and crystallization tendency of drug molecules

Effects of di- and polysaccharide formulations and storage conditions on survival of freeze-dried Sphingobium sp.

Onneby, Karin; Pizzul, Leticia; Bjerketorp, Joakim; Mahlin, Denny et al.

Part of World Journal of Microbiology & Biotechnology, p. 1399-1408, 2013.

DOI for Effects of di- and polysaccharide formulations and storage conditions on survival of freeze-dried Sphingobium sp.

Factors Affecting Enzymatic Degradation of Microgel-Bound Peptides

Mansson, Ronja; Frenning, Göran; Malmsten, Martin

Part of Biomacromolecules, p. 2317-2325, 2013.

DOI for Factors Affecting Enzymatic Degradation of Microgel-Bound Peptides

The influence of rolling friction on the shear behaviour of non-cohesive pharmaceutical granules: An experimental and numerical investigation

Persson, Ann-Sofie; Frenning, Göran

Part of European Journal of Pharmaceutical Sciences, p. 241-250, 2013.

DOI for The influence of rolling friction on the shear behaviour of non-cohesive pharmaceutical granules: An experimental and numerical investigation Download full text (pdf) of The influence of rolling friction on the shear behaviour of non-cohesive pharmaceutical granules: An experimental and numerical investigation

The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction

Nordström, Josefina; Persson, Ann-Sofie; Lazorova, Lucia; Frenning, Göran et al.

Part of International Journal of Pharmaceutics, p. 3-12, 2013.

DOI for The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction Download full text (pdf) of The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction

Towards a mechanistic model for the interaction between plastically deforming particles under confined conditions: A numerical and analytical analysis

Frenning, Göran

Part of Materials letters (General ed.), p. 365-368, 2013.

DOI for Towards a mechanistic model for the interaction between plastically deforming particles under confined conditions: A numerical and analytical analysis Download full text (pdf) of Towards a mechanistic model for the interaction between plastically deforming particles under confined conditions: A numerical and analytical analysis

Mechanism of Amorphisation of Micro-Particles of Griseofulvin During Powder Flow in a Mixer

Pazesh, Samaneh; Höckerfelt, Mina Heidarian; Berggren, Jonas; Bramer, Tobias et al.

Part of Journal of Pharmaceutical Sciences, p. 4036-4045, 2013.

DOI for Mechanism of Amorphisation of Micro-Particles of Griseofulvin During Powder Flow in a Mixer

Early drug development predictions of glass-forming ability and physical stability of drugs

Mahlin, Denny; Bergström, Christel A. S.

Part of European Journal of Pharmaceutical Sciences, p. 323-332, 2013.

DOI for Early drug development predictions of glass-forming ability and physical stability of drugs Download full text (pdf) of Early drug development predictions of glass-forming ability and physical stability of drugs

A comparison between two powder compaction parameters of plasticity: The effective medium A parameter and the Heckel 1/K parameter

Mahmoodi, Foad; Klevan, Ingvild; Nordström, Josefina; Alderborn, Göran et al.

Part of International Journal of Pharmaceutics, p. 295-299, 2013.

DOI for A comparison between two powder compaction parameters of plasticity: The effective medium A parameter and the Heckel 1/K parameter Download full text (pdf) of A comparison between two powder compaction parameters of plasticity: The effective medium A parameter and the Heckel 1/K parameter

Effect of degree of methoxylation and particle size on compression properties and compactibility of pectin powders

Salbu, Linda; Bauer-Brandl, Annette; Alderborn, Göran; Tho, Ingunn

Part of Pharmaceutical development and technology (Print), p. 333-343, 2012.

DOI for Effect of degree of methoxylation and particle size on compression properties and compactibility of pectin powders

Pharmacokinetics of levodopa/carbidopa microtablets versus levodopa/benserazide and levodopa/carbidopa in healthy volunteers

Nyholm, Dag; Lewander, Tommy; Gomes-Trolin, Cecilia; Bäckström, Tobias et al.

Part of Clinical neuropharmacology, p. 111-117, 2012.

DOI for Pharmacokinetics of levodopa/carbidopa microtablets versus levodopa/benserazide and levodopa/carbidopa in healthy volunteers

An experimental evaluation of the accuracy to simulate granule bed compression using the discrete element method

Persson, Ann-Sofie; Frenning, Göran

Part of Powder Technology, p. 249-256, 2012.

DOI for An experimental evaluation of the accuracy to simulate granule bed compression using the discrete element method Download full text (pdf) of An experimental evaluation of the accuracy to simulate granule bed compression using the discrete element method

An experimental evaluation of an effective medium based compaction equation

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Part of European Journal of Pharmaceutical Sciences, p. 49-55, 2012.

DOI for An experimental evaluation of an effective medium based compaction equation Download full text (pdf) of An experimental evaluation of an effective medium based compaction equation

A protocol for the classification of powder compression characteristics

Nordstrom, Josefina; Kievan, Ingvild; Alderborn, Göran

Part of European journal of pharmaceutics and biopharmaceutics, p. 209-216, 2012.

DOI for A protocol for the classification of powder compression characteristics

mRNA expression of drug-transporting proteins along the human intestine and comparison with expression in Caco-2 cells

Englund, Gunilla; Rorsman, Fredrik; Rönnblom, Anders; Lazorova, Lucia et al.

2012.

Gel formulations containing catanionic vesicles composed of alprenolol and SDS: effects of drug release and skin penetration on aggregate structure

Dew, Noel; Edwards, Katarina; Eriksson, Jonny; Edsman, Katarina et al.

Part of Colloids and Surfaces B, p. 53-60, 2012.

DOI for Gel formulations containing catanionic vesicles composed of alprenolol and SDS: effects of drug release and skin penetration on aggregate structure

A model describing the internal structure of core/shell hydrogels

Gernandt, Jonas; Frenning, Göran; Richtering, Walter; Hansson, Per

Part of Soft Matter, p. 10327-10338, 2011.

DOI for A model describing the internal structure of core/shell hydrogels

The Release of Catanionic Mixtures Embedded in Gels: An Approximate Analytical Analysis

Frenning, Göran; Gråsjö, Johan; Hansson, Per

Part of AIChE Journal, p. 1402-1408, 2011.

DOI for The Release of Catanionic Mixtures Embedded in Gels: An Approximate Analytical Analysis Download full text (pdf) of The Release of Catanionic Mixtures Embedded in Gels: An Approximate Analytical Analysis

Flowability of surface modified pharmaceutical granules: A comparative experimental and numerical study

Persson, Ann-Sofie; Alderborn, Göran; Frenning, Göran

Part of European Journal of Pharmaceutical Sciences, p. 199-209, 2011.

DOI for Flowability of surface modified pharmaceutical granules: A comparative experimental and numerical study Download full text (pdf) of Flowability of surface modified pharmaceutical granules: A comparative experimental and numerical study

Degree of compression as a potential process control tool of tablet tensile strength

Nordström, Josefina; Alderborn, Göran

Part of Pharmaceutical development and technology (Print), p. 599-608, 2011.

DOI for Degree of compression as a potential process control tool of tablet tensile strength

Modeling structure-function relationships for diffusive drug transport in inert porous geopolymer matrices

Jämstorp, Erik; Strømme, Maria; Frenning, Göran

Part of Journal of Pharmaceutical Sciences, p. 4338-4348, 2011.

DOI for Modeling structure-function relationships for diffusive drug transport in inert porous geopolymer matrices Download full text (pdf) of Modeling structure-function relationships for diffusive drug transport in inert porous geopolymer matrices

Impact of matrix properties on survival of freeze-dried bacteria

Wessman, Per; Mahlin, Denny; Akhtar, Sultan; Rubino, Stefano et al.

Part of Journal of the Science of Food and Agriculture, p. 2518-2528, 2011.

DOI for Impact of matrix properties on survival of freeze-dried bacteria

Novel Gel Formulations with Catanionic Aggregates Enable Prolonged Drug Release and Reduced Skin Permeation

Dew, Noel; Edsman, Katarina; Björk, Erik

Part of Journal of Pharmacy and Pharmacology (JPP), p. 1265-1273, 2011.

DOI for Novel Gel Formulations with Catanionic Aggregates Enable Prolonged Drug Release and Reduced Skin Permeation

Effect of spherical-agglomerate strength on the distribution of force during uniaxial compression

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Part of Powder Technology, p. 283-290, 2011.

DOI for Effect of spherical-agglomerate strength on the distribution of force during uniaxial compression Download full text (pdf) of Effect of spherical-agglomerate strength on the distribution of force during uniaxial compression

Toward In Silico Prediction of Glass-Forming Ability from Molecular Structure Alone: A Screening Tool in Early Drug Development

Mahlin, Denny; Ponnambalam, Sopana; Hockerfelt, Mina Heidarian; Bergström, Christel A. S.

Part of Molecular Pharmaceutics, p. 498-506, 2011.

DOI for Toward In Silico Prediction of Glass-Forming Ability from Molecular Structure Alone: A Screening Tool in Early Drug Development

Unveiling the complex electronic structure of amorphous metal oxides

Århammar, Cecilia; Pietzsch, Annette; Bock, Nicolas; Holmström, Erik et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 6355-6360, 2011.

DOI for Unveiling the complex electronic structure of amorphous metal oxides

Pharmaceutical micro-particles give amorphous sucrose higher physical stability

Hellrup, Joel; Mahlin, Denny

Part of International Journal of Pharmaceutics, p. 96-103, 2011.

DOI for Pharmaceutical micro-particles give amorphous sucrose higher physical stability

Compression mechanics of granule beds: A combined finite/discrete element study

Frenning, Göran

Part of Chemical Engineering Science, p. 2464-2471, 2010.

DOI for Compression mechanics of granule beds: A combined finite/discrete element study Download full text (pdf) of Compression mechanics of granule beds: A combined finite/discrete element study

A statistical approach to evaluate the potential use of compression parameters for classification of pharmaceutical powder materials

Klevan, Ingvild; Nordström, Josefina; Tho, Ingunn; Alderborn, Göran

Part of European journal of pharmaceutics and biopharmaceutics, p. 425-435, 2010.

DOI for A statistical approach to evaluate the potential use of compression parameters for classification of pharmaceutical powder materials

Structural effects caused by spray- and freeze-drying of liposomes and bilayer disks

Wessman, Per; Edwards, Katarina; Mahlin, Denny

Part of Journal of Pharmaceutical Sciences, p. 2032-2048, 2010.

DOI for Structural effects caused by spray- and freeze-drying of liposomes and bilayer disks

Understanding polymer-lipid solid dispersions-The properties of incorporated lipids govern the crystallisation behaviour of PEG

Unga, Johan; Matsson, Pär; Mahlin, Denny

Part of International Journal of Pharmaceutics, p. 61-70, 2010.

DOI for Understanding polymer-lipid solid dispersions-The properties of incorporated lipids govern the crystallisation behaviour of PEG

Effect of lubrication on the distribution of force between spherical agglomerates during compression

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Part of Powder Technology, p. 69-74, 2010.

DOI for Effect of lubrication on the distribution of force between spherical agglomerates during compression Download full text (pdf) of Effect of lubrication on the distribution of force between spherical agglomerates during compression

Differential effects of polymers PVP90 and Ficoll400 on storage stability and viability of Lactobacillus coryniformis Si3 freeze-dried in sucrose

Schoug, Å.; Mahlin, Denny; Jonson, M.; Håkansson, S.

Part of Journal of Applied Microbiology, p. 1032-1040, 2010.

DOI for Differential effects of polymers PVP90 and Ficoll400 on storage stability and viability of Lactobacillus coryniformis Si3 freeze-dried in sucrose

Proton Absorption in As-Synthesized Mesoporous Silica Nanoparticles as a Structure-Function Relationship Probing Mechanism

Strømme, Maria; Atluri, Rambabu; Brohede, Ulrika; Frenning, Göran et al.

Part of Langmuir, p. 4306-4310, 2009.

DOI for Proton Absorption in As-Synthesized Mesoporous Silica Nanoparticles as a Structure-Function Relationship Probing Mechanism

Relating solubility data of parabens in liquid PEG 400 to the behaviour of PEG 4000-parabens solid dispersions

Unga, Johan; Tajarobi, Farhad; Norder, Ove; Frenning, Göran et al.

Part of European journal of pharmaceutics and biopharmaceutics, p. 260-268, 2009.

DOI for Relating solubility data of parabens in liquid PEG 400 to the behaviour of PEG 4000-parabens solid dispersions

Electronic structure of water molecules confined in a micelle lattice

Gråsjö, Johan; Andersson, Egil; Forsberg, Johan; Aziz, Emad F. et al.

Part of Journal of Physical Chemistry B, p. 8201-8205, 2009.

DOI for Electronic structure of water molecules confined in a micelle lattice

Dry mixing transformed micro-particles of a drug from a highly crystalline to a highly amorphous state

Höckerfelt, Mina Heidarian; Nyström, Christer; Alderborn, Göran

Part of Pharmaceutical development and technology (Print), p. 233-239, 2009.

DOI for Dry mixing transformed micro-particles of a drug from a highly crystalline to a highly amorphous state

On the physical interpretation of the initial bending of a Shapiro-Konopicky-Heckel compression profile

Klevan, Ingvild; Nordström, Josefina; Bauer-Brandl, Annette; Alderborn, Göran

Part of European journal of pharmaceutics and biopharmaceutics, p. 395-401, 2009.

DOI for On the physical interpretation of the initial bending of a Shapiro-Konopicky-Heckel compression profile

Clinical study shows improved absorption of desmopressin with novel formulation

Fransén, Nelly; Bredenberg, Susanne; Björk, Erik

Part of Pharmaceutical research, p. 1618-1625, 2009.

DOI for Clinical study shows improved absorption of desmopressin with novel formulation

Effective Kawakita parameters for binary mixtures

Frenning, Göran; Nordström, Josefina; Alderborn, Göran

Part of Powder Technology, p. 270-275, 2009.

DOI for Effective Kawakita parameters for binary mixtures

A particle rearrangement index based on the Kawakita powder compression equation

Nordström, Josefina; Klevan, Ingvild; Alderborn, Göran

Part of Journal of Pharmaceutical Sciences, p. 1053-1063, 2009.

DOI for A particle rearrangement index based on the Kawakita powder compression equation

Implications of regular solution theory on the release mechanism of catanionic mixtures from gels

Bramer, Tobias; Frenning, Göran; Gråsjö, Johan; Edsman, Katarina et al.

Part of Colloids and Surfaces B, p. 214-225, 2009.

DOI for Implications of regular solution theory on the release mechanism of catanionic mixtures from gels

Angular anisotropy in resonant inelastic soft X-ray scattering of liquid water

Forsberg, Johan; Gråsjö, Johan; Brena, Barbara; Nordgren, Joseph et al.

Part of Physical Review B. Condensed Matter and Materials Physics, p. 132203-, 2009.

DOI for Angular anisotropy in resonant inelastic soft X-ray scattering of liquid water

The multiple depletion curves method provides accurate estimates of intrinsic clearance (CLint), maximum velocity of the metabolic reaction (Vmax), and Michaelis constant (Km): accuracy and robustness evaluated through experimental data and Monte Carlo simulations

Sjögren, Erik; Lennernäs, Hans; Andersson, Tommy B; Gråsjö, Johan et al.

Part of Drug Metabolism And Disposition, p. 47-58, 2009.

DOI for The multiple depletion curves method provides accurate estimates of intrinsic clearance (CLint), maximum velocity of the metabolic reaction (Vmax), and Michaelis constant (Km): accuracy and robustness evaluated through experimental data and Monte Carlo simulations

A novel powder sample holder for the determination of glass transition temperatures by DMA

Mahlin, Denny; Wood, John; Hawkins, Nicholas; Mahey, Jas et al.

Part of International Journal of Pharmaceutics, p. 120-125, 2009.

DOI for A novel powder sample holder for the determination of glass transition temperatures by DMA

Local Electronic Structure of Functional Groups in Glycine As Anion, Zwitterion, and Cation in Aqueous Solution

Gråsjö, Johan; Andersson, Egil; Forsberg, Johan; Duda, Laurent et al.

Part of Journal of Physical Chemistry B, p. 16002-16006, 2009.

DOI for Local Electronic Structure of Functional Groups in Glycine As Anion, Zwitterion, and Cation in Aqueous Solution

Aspects of pharmaceutical physics

Frenning, Göran; Alderborn, Göran

Part of Modern Pharmaceutics, Volume 2, 2009.

DOI for Aspects of pharmaceutical physics

An effective-medium analysis of confined compression of granular materials

Frenning, Göran; Mahmoodi, Foad; Nordström, Josefina; Alderborn, Göran

Part of Powder Technology, p. 228-232, 2009.

DOI for An effective-medium analysis of confined compression of granular materials

Order and disorder in powder mixtures: Spatial distribution functions as tools to assess powder homogeneity

Mihranyan, Albert; Frenning, Göran; Fransén, Nelly; Welch, Ken et al.

Part of Particle & particle systems characterization, p. 397-405, 2009.

DOI for Order and disorder in powder mixtures: Spatial distribution functions as tools to assess powder homogeneity

Ionic motion in polypyrrole-cellulose composites: Trap release mechanism during potentiostatic reduction

Strömme, Maria; Frenning, Göran; Razaq, Aamir; Gelin, Kristina et al.

Part of Journal of Physical Chemistry B, p. 4582-4589, 2009.

DOI for Ionic motion in polypyrrole-cellulose composites: Trap release mechanism during potentiostatic reduction Download full text (pdf) of Ionic motion in polypyrrole-cellulose composites: Trap release mechanism during potentiostatic reduction

Determining the static dielectric permittivity of ion conducting materials

Gråsjö, Johan; Welch, Ken; Strömme, Maria

Part of Applied Physics Letters, p. 092901-1, 2008.

DOI for Determining the static dielectric permittivity of ion conducting materials

An efficient finite/discrete element procedure for simulating compression of 3D particle assemblies

Frenning, Göran

Part of Computer methods in applied mechanics and engineering, p. 4266-4272, 2008.

DOI for An efficient finite/discrete element procedure for simulating compression of 3D particle assemblies

On the role of granule yield strength for the compactibility of granular solids

Nordström, Josefina; Welch, Ken; Frenning, Göran; Alderborn, Göran

Part of Journal of Pharmaceutical Sciences, p. 4807-4814, 2008.

DOI for On the role of granule yield strength for the compactibility of granular solids

Physicochemical interactions between drugs and superdisintegrants

Fransén, Nelly; Morin, Malin; Björk, Erik; Edsman, Katarina

Part of Journal of Pharmacy and Pharmacology (JPP), p. 1583-9, 2008.

DOI for Physicochemical interactions between drugs and superdisintegrants

On the physical interpretation of the Kawakita and Adams parameters derived from confined compression of granular solids

Nordström, Josefina; Welch, Ken; Frenning, Göran; Alderborn, Göran

Part of Powder Technology, p. 424-435, 2008.

DOI for On the physical interpretation of the Kawakita and Adams parameters derived from confined compression of granular solids

Effect of surface energy on powder compactibility

Fichtner, Frauke; Mahlin, Denny; Welch, Ken; Gaisford, Simon et al.

Part of Pharmaceutical research, p. 2750-9, 2008.

DOI for Effect of surface energy on powder compactibility

Changes in the mucoadhesion of powder formulations after drug application investigated with a simplified method

Fransén, Nelly; Björk, Erik; Edsman, Katarina

Part of Journal of Pharmaceutical Sciences, p. 3855-3864, 2008.

DOI for Changes in the mucoadhesion of powder formulations after drug application investigated with a simplified method

Spectral analysis of force fluctuations during probe penetration into cohesive powders

Frenning, Göran; Alderborn, Göran; Kish, Laszlo B.; Mahlin, Denny

Part of Powder Technology, p. 62-67, 2008.

DOI for Spectral analysis of force fluctuations during probe penetration into cohesive powders

Mechanical strength of tablets

Alderborn, Göran; Frenning, Göran

Part of Pharmaceutical Dosage Forms, 2008.

Photoinduced Formation of N₂ Molecules in Ammonium Compounds

Aziz, Emad F; Gråsjö, Johan; Forsberg, Johan; Andersson, Egil et al.

Part of Journal of Physical Chemistry A, p. 9662-9669, 2007.

DOI for Photoinduced Formation of N₂ Molecules in Ammonium Compounds

The use of extragranular disintegrants in multiple-unit tablet formulations: effect on compressibility, compactibility and disintegration

Adane, M.; Gebre-Mariam, T; Alderborn, Göran; Frenning, Göran

Part of Journal of drug delivery science and technology, p. 279-284, 2007.

Analysis of pharmaceutical powder compaction using multiplicative hyperelasto-plastic theory

Frenning, Göran

Part of Powder Technology, p. 103-112, 2007.

DOI for Analysis of pharmaceutical powder compaction using multiplicative hyperelasto-plastic theory

Percolative drug diffusion from cylindrical matrix systems with unsealed boundaries

Brohede, Ulrika; Valizadeh, Sima; Strømme, Maria; Frenning, Göran

Part of Journal of Pharmaceutical Sciences, p. 3087-3099, 2007.

DOI for Percolative drug diffusion from cylindrical matrix systems with unsealed boundaries

Drug release from compacted single inert matrix agglomerates

Fichtner, Frauke; Frenning, Göran; Alderborn, Göran

Part of Journal of Drug Delivery Science and Technology, p. 273-277, 2007.

Effect of preparation method on compactability of paracetamol granules and agglomerates

Fichtner, Frauke; Rasmuson, Åke; Ålander, Eva; Alderborn, Göran

Part of International Journal of Pharmaceutics, p. 148-158, 2007.

DOI for Effect of preparation method on compactability of paracetamol granules and agglomerates

The in vitro transport of dihydroergotamine across porcine nasal respiratory and olfactory mucosa and the effect of a novel powder formulation

Fransén, Nelly; Espefält Westin, Ulrika; Nyström, Christer; Björk, Erik

Part of Journal of Drug Delivery Science and Technology, p. 267-271, 2007.

Development and characterisation of interactive mixtures with a fine-particulate mucoadhesive carrier for nasal drug delivery

Fransén, Nelly; Björk, Erik; Nyström, Christer

Part of European journal of pharmaceutics and biopharmaceutics, p. 370-376, 2007.

DOI for Development and characterisation of interactive mixtures with a fine-particulate mucoadhesive carrier for nasal drug delivery