What determines drug absorption, disposition and efficacy?
Barriers to drug absorption and delivery
We develop tools and study the mechanisms affecting the drug’s path through the body.
Cellular drug disposition and delivery
We have established and developed cell models for prediction of drug transport, metabolism and cellular bioavailability
Computational drug absorption and disposition
We use computational modeling and simulation to shed light on the cellular and molecular mechanisms of drug absorption and disposition
proteomics and bioinformatics
We use proteomics to accurately detect, quantify and analyze the cellular proteome with emphasis on drug transporting and metabolizing proteines.