Publications 2017
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A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.
Part of Journal of Pharmaceutical Sciences, p. 2909-2913, 2017.
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Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid
Part of Journal of Physical Chemistry B, p. 10869-10881, 2017.
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Controlled Suspensions Enable Rapid Determinations of Intrinsic Dissolution Rate and Apparent Solubility of Poorly Water-Soluble Compounds
Part of Pharmaceutical research, p. 1805-1816, 2017.
DOI for Controlled Suspensions Enable Rapid Determinations of Intrinsic Dissolution Rate and Apparent Solubility of Poorly Water-Soluble Compounds Download full text (pdf) of Controlled Suspensions Enable Rapid Determinations of Intrinsic Dissolution Rate and Apparent Solubility of Poorly Water-Soluble Compounds
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Enhanced release of poorly water-soluble drugs from synergy between mesoporous magnesium carbonate and polymers
Part of International Journal of Pharmaceutics, p. 183-190, 2017.
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Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1
Part of Journal of Medicinal Chemistry, p. 2148-2154, 2017.
DOI for Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1
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Intracellular drug bioavailability: a new predictor of system dependent drug disposition
Part of Scientific Reports, p. 1-12, 2017.
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Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method
Part of Molecular Pharmaceutics, p. 4161-4169, 2017.
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Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways
Part of Journal of Controlled Release, p. 193-202, 2017.
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Molecular Structuring and Phase Transition of Lipid-Based Formulations upon Water Dispersion: A Coarse-Grained Molecular Dynamics Simulation Approach
Part of Molecular Pharmaceutics, p. 4145-4153, 2017.
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Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors
Part of Journal of Medicinal Chemistry, p. 4279-4292, 2017.
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Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery
Part of Proceedings of the National Academy of Sciences of the United States of America, p. E6231-E6239, 2017.
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Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2)
Part of European Journal of Pharmaceutical Sciences, p. 70-76, 2017.
DOI for Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2)
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The Need for Restructuring the Disordered Science of Amorphous Drug Formulations
Part of Pharmaceutical Research, p. 1754-1772, 2017.
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Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes
Part of Molecular Pharmaceutics, p. 3142-3151, 2017.
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