Publications 2016
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50 years of oral lipid-based formulations: Provenance, progress and future perspectives
Part of Advanced Drug Delivery Reviews, p. 167-194, 2016.
DOI for 50 years of oral lipid-based formulations: Provenance, progress and future perspectives
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A Tribute to Ronald T. Borchardt-Teacher, Mentor, Scientist, Colleague, Leader, Friend, and Family Man
Part of Journal of Pharmaceutical Sciences, p. 370-385, 2016.
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Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures
Part of ACS Chemical Neuroscience, p. 1383-1392, 2016.
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CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
Part of Nature Communications, 2016.
DOI for CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil Download full text (pdf) of CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
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Comparative proteome analysis of human liver tissue and isolated hepatocytes: application to predictions of hepatic pitavastatin uptake clearance
Part of Drug metabolism reviews (Softcover ed.), p. 96-96, 2016.
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Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9
Part of Journal of Pharmaceutical Sciences, p. 1017-1021, 2016.
DOI for Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9
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Compromised in vitro dissolution and membrane transport of multidrug amorphous formulations.
Part of Journal of Controlled Release, p. 172-182, 2016.
DOI for Compromised in vitro dissolution and membrane transport of multidrug amorphous formulations.
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Computational prediction of formulation strategies for beyond-rule-of-5 compounds
Part of Advanced Drug Delivery Reviews, p. 6-21, 2016.
DOI for Computational prediction of formulation strategies for beyond-rule-of-5 compounds Download full text (pdf) of Computational prediction of formulation strategies for beyond-rule-of-5 compounds
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Development of MS- based immunoassays for Cytochrome P450 and transporter quantification
Part of Naunyn-Schmiedeberg's Archives of Pharmacology, p. S47-S47, 2016.
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Diffusion-Controlled Drug Release from the Mesoporous Magnesium Carbonate Upsalite®
Part of Journal of Pharmaceutical Sciences, p. 657-663, 2016.
DOI for Diffusion-Controlled Drug Release from the Mesoporous Magnesium Carbonate Upsalite®
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Direct Measurement of Intracellular Compound Concentration by RapidFire Mass Spectrometry Offers Insights into Cell Permeability
Part of Journal of Biomolecular Screening, p. 156-164, 2016.
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Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1
Part of Journal of Medicinal Chemistry, p. 1140-1148, 2016.
DOI for Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1
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Global proteome changes in liver tissue 6 weeks after FOLFOX treatment of colorectal cancer liver metastases
Part of PROTEOMES, 2016.
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Impact of drug transporters on intracellular unbound drug concentrations
Part of Drug metabolism reviews (Softcover ed.), p. 147-147, 2016.
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In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes
Part of Journal of Proteomics, p. 234-247, 2016.
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Interlaboratory Validation of Small-Scale Solubility and Dissolution Measurements of Poorly Water-Soluble Drugs
Part of Journal of Pharmaceutical Sciences, p. 2864-2872, 2016.
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Lipophilicity in Drug Development: Too Much or Not Enough?
Part of AAPS Journal, p. 1095-1100, 2016.
DOI for Lipophilicity in Drug Development: Too Much or Not Enough?
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Mechanistic modeling of hepatic pitavastatin disposition: a proteomics-informed bottom-up approach
Part of Drug metabolism reviews (Softcover ed.), p. 56-57, 2016.
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Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach
Part of Drug Metabolism And Disposition, p. 505-516, 2016.
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New cell-based approaches for better predictions of drug transport and cellular drug exposure
Part of Drug metabolism reviews (Softcover ed.), p. 7-7, 2016.
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Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues
Part of Advanced Drug Delivery Reviews, p. 256-276, 2016.
DOI for Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues Download full text (pdf) of Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues
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Partitioning into Colloidal Structures of Fasted State Intestinal Fluid Studied by Molecular Dynamics Simulations
Part of Langmuir, p. 12732-12740, 2016.
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Protein quantification of human hepatic drug transporters and metabolizing enzymes: an inter-laboratory and methodological comparison
Part of Drug metabolism reviews (Softcover ed.), p. 98-98, 2016.
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Rapid determination of drug solubilization versus supersaturation in natural and digested lipids
Part of International Journal of Pharmaceutics, p. 164-174, 2016.
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Structural and conformational determinants of macrocycle cell permeability
Part of Nature Chemical Biology, p. 1065-+, 2016.
DOI for Structural and conformational determinants of macrocycle cell permeability
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Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions
Part of Analytical Biochemistry, p. 82-88, 2016.
DOI for Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions Download full text (pdf) of Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions
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Supersaturation of poorly soluble drugs induced by mesoporous magnesium carbonate
Part of European Journal of Pharmaceutical Sciences, p. 468-474, 2016.
DOI for Supersaturation of poorly soluble drugs induced by mesoporous magnesium carbonate
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The Need for Speed-Kinetic Limits of Drug Transporters
Part of TIPS - Trends in Pharmacological Sciences, p. 243-245, 2016.
DOI for The Need for Speed-Kinetic Limits of Drug Transporters
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The Pro-inflammatory Cytokine Interleukin-6 Regulates Nanoparticle Transport Across Model Follicle-Associated Epithelium Cells
Part of Journal of Pharmaceutical Sciences, p. 2099-2104, 2016.
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The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition
Part of Journal of Pharmaceutical Sciences, p. 817-827, 2016.
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Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity
Part of Journal of Medicinal Chemistry, p. 2094-2108, 2016.
DOI for Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity
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To attach or not to attach: factors behind variable adhesion properties of cryopreserved human hepatocytes
Part of Drug metabolism reviews (Softcover ed.), p. 103-103, 2016.
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Tools for Early Prediction of Drug Loading in Lipid-Based Formulations
Part of Molecular Pharmaceutics, p. 251-261, 2016.
DOI for Tools for Early Prediction of Drug Loading in Lipid-Based Formulations
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Understanding the Challenge of Beyond-Rule-of-5 Compounds Preface
Part of Advanced Drug Delivery Reviews, p. 1-5, 2016.
DOI for Understanding the Challenge of Beyond-Rule-of-5 Compounds Preface