News from the Drug Delivery Group

The program for the 12th Pharmaceutical Profiling Symposium is now finalised and we are happy to announce the full list of confirmed speakers and their respective topics.

We would like to congratulate Madlen Hubert for being promoted to Associate Professor (docent)! Very well done and a hard-earned achievement!

The Valborg Jacobsons fond supports Madlen’s research with a grant of 200’000 SEK to develop human gut models for improved prediction of the in vivo performance of advanced oral medicines. Congratulations!

SweDeliver is now recruiting two PhD Students in Molecular Pharmaceutics. Welcome to submit your application no later than 18 February 2022.

The 11^th Symposium on Pharmaceutical Profiling in Drug Discovery and Development on January 27, 2022 will be held as a virtual meeting! Don’t miss to register before Jan 13.

The new article by Rosita Kneiszl, Shakhawath Hossain and Per Larsson was selected as today's ACS (American Chemical Society) Editors' Choice among articles from +60 peer-reviewed journals.

Prof. Christel Bergström gave her inaugural lecture November 16, 2021. The video is now available.

The registration for the upcoming 11^th Symposium on Pharmaceutical Profiling in Drug Discovery and Development on January 27, 2022 is now open.

The Editorial Staff and the American Pharmacists Association are for the first time choosing outstanding early career scientists for publishing their most original and significant scientific findings in the Journal of Pharmaceutical Sciences(JPharmSci®) in 2021. Alexandra Teleki is one of the ten researchers who were recognised worldwide! Congratulations!

We are delighted to announce the date for the upcoming Symposium on Pharmaceutical Profiling in Drug Discovery and Development on January 27, 2022 in Uppsala, Sweden. Keynote speakers and registration details will be announced shortly.

Per Artursson, Christel Bergström, Madlen Hubert and Pawel Baranczewski

Drug Delivery Group, Department of Pharmacy, Uppsala University

The research group Molecular Pharmaceutics are looking to recruit a PhD student for a project to develop a generic nanosized drug delivery platform for optimal absorption of antibiotics with minimal intestinal side effects.

SweDeliver is recruiting a researcher in molecular pharmaceutics for the project Structural characterization of formulated macromolecular drugs with lipids in response to dilution, digestion and permeation. Submit your application no later than 16 April 2021.

The BLT group is looking for new postdoctoral researcher. Join our multidisciplinary team as a post-doc focusing on lipid nanoparticles for oral drug delivery.
See advertisement for details, apply before 30 April 2021.

The Journal of Pharmaceutical Sciences has highlighted the original research article titled "Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease" in their quartely summary of "Most Original and Most Significant Scientific Findings".

The article is authored by Shno Asad, Christine Wegler, David Ahl, Christel A.S. Bergström, Mia Phillipson, Per Artursson and Alexandra Teleki.

"Understanding what happens in the gut is crucial to the success of oral medications"

Read more about the ERC financed (completed) "Intestinanos" project here: https://cordis.europa.eu/article/id/429242-building-virtual-intestine-to-fine-tune-the-formulations-of-new-drugs

The upcoming 11^th Symposium on Pharmaceutical Profiling in Drug Discovery and Development at Uppsala University is postponed to January 2022 due to current pandemic situation.

Are you interested in joining our team for a summer research project? Apotekarsocieteten has scholarships supporting 5-7 weeks of research studies. Reach out to us to discuss interesting project ideas! Dead-line for application is Jan 31.

Per Artursson, Olof Eriksson, Hans Lennernäs and Ola Spjuth are granted 16.68 million from the Swedish research Swedish Research Council for research involving medicine and health. The grant will be received during 2020 and four years ahead.

Professor Per Artursson appointed Giant of Pharmaceutical Sciences by the Journal of Pharmaceutical Sciences, which is the world's oldest pharmaceutical journal.

Maria Karlgren has received the 2020 IQ Consortium and AAALAC International Global 3Rs Award based on the scientific research paper “A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.”

With a new and more accurate computational model for how the drug rosuvastatin (Crestor ®) is taken up and eliminated in the liver, researchers at Uppsala University paves the way for more efficient drug development and future treatment methods.

With the Nobel Prize-winning technology CRISPR-Cas9, researchers at Uppsala University are creating new components for more efficient drug development with fewer animal experiments.

We are very delighted to receive the news that the Family Erling Persson Foundation will continue to support our project on “Personalized medications for children suffering from severe diseases”. This is a fantastic collaborative project between our group, Prof Maria Strømme´s group at the Ångström laboratory and the Children’s Hospital in Uppsala.

Assistant Professor Per Larsson has been granted project funds for development of online learning methods.

The Artursson and Bergström group have together donated personal protective equipment (PPE) including safety glasses, mouth protection and 12,500 gloves to assist the staff at the Uppsala University Hospital during the Covid-19 pandemic.

The Artursson research group is supporting the fight against the corona virus by donating cells from our cell culture facility to other research groups working with Covid-19 projects.

In the third round (2019) for the European Research Council's (ERC) "’Proof of Concept Grant", Christel Bergström has been awarded a grant for further development of the digestion/permeation chamber ENA to meet industrial needs.

Shno Asad, PhD student at the Department of Pharmacy at Uppsala University, was awarded the prize for best poster at ICONAN 2019 (International Conference on Nanomedicine and Nanobiotechnology). The conference was held between 16-18 October i Munich.

An interview with Dr. Christel Bergström was broadcast this Thursday in Swedish TV and radio news. In the interview, Dr. Bergström describes the ongoing project to improve the pediatric care by the use of 3D-printed drug dosage forms. See below for links to the features (in Swedish).

Gattefossé North Americas "2018 Award for Excellence in Research & Development with Lipid Excipients" has been awarded to Dr. Christel Bergström. She received this award for her work with modelling and predicting solubility of drugs in lipid systems.