Senaste publikationer
Publikationer
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Active Uptake of Oxycodone at Both the Blood-Cerebrospinal Fluid Barrier and The Blood-Brain Barrier without Sex Differences: A Rat Microdialysis Study
Ingår i Pharmaceutical research, 2023.
DOI för Active Uptake of Oxycodone at Both the Blood-Cerebrospinal Fluid Barrier and The Blood-Brain Barrier without Sex Differences: A Rat Microdialysis Study Ladda ner fulltext (pdf) av Active Uptake of Oxycodone at Both the Blood-Cerebrospinal Fluid Barrier and The Blood-Brain Barrier without Sex Differences: A Rat Microdialysis Study
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Differential Blood-Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro
Ingår i Pharmaceutics, 2023.
DOI för Differential Blood-Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro Ladda ner fulltext (pdf) av Differential Blood-Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro
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Possible Extraction of Drugs from Lung Tissue During Broncho-alveolar Lavage Suggest Uncertainty in the Procedure's Utility for Quantitative Assessment of Airway Drug Exposure
Ingår i Journal of Pharmaceutical Sciences, s. 852-858, 2022.
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Professor Margareta Hammarlund-Udenaes - Humbled Scientist Shaping Modern Neuropharmacokinetics
Ingår i Pharmaceutical research, s. 1283-1289, 2022.
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Professor Margareta Hammarlund-Udenaes: a Modern and Visionary Mentor
Ingår i Pharmaceutical research, s. 1291-1296, 2022.
DOI för Professor Margareta Hammarlund-Udenaes: a Modern and Visionary Mentor
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Unbound Brain-to-Plasma Partition Coefficient, K-p,K-uu,K-brain-a Game Changing Parameter for CNS Drug Discovery and Development
Ingår i Pharmaceutical research, s. 1321-1341, 2022.
DOI för Unbound Brain-to-Plasma Partition Coefficient, K-p,K-uu,K-brain-a Game Changing Parameter for CNS Drug Discovery and Development Ladda ner fulltext (pdf) av Unbound Brain-to-Plasma Partition Coefficient, K-p,K-uu,K-brain-a Game Changing Parameter for CNS Drug Discovery and Development
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Understanding the Blood-Brain Barrier and Beyond: Challenges and Opportunities for Novel CNS Therapeutics
Ingår i Clinical Pharmacology and Therapeutics, s. 758-773, 2022.
DOI för Understanding the Blood-Brain Barrier and Beyond: Challenges and Opportunities for Novel CNS Therapeutics Ladda ner fulltext (pdf) av Understanding the Blood-Brain Barrier and Beyond: Challenges and Opportunities for Novel CNS Therapeutics
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Deep learning and conformal prediction for hierarchical analysis of large-scale whole-slide tissue images
Ingår i IEEE journal of biomedical and health informatics, s. 371-380, 2021.
DOI för Deep learning and conformal prediction for hierarchical analysis of large-scale whole-slide tissue images Ladda ner fulltext (pdf) av Deep learning and conformal prediction for hierarchical analysis of large-scale whole-slide tissue images
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Lung pharmacokinetics of inhaled and systemic drugs: A clinical evaluation
Ingår i British Journal of Pharmacology, s. 4440-4451, 2021.
DOI för Lung pharmacokinetics of inhaled and systemic drugs: A clinical evaluation
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Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier.
Ingår i Molecular Psychiatry, s. 7732-7745, 2021.
DOI för Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier. Ladda ner fulltext (pdf) av Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier.
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Brain Distribution of Drugs:: Pharmacokinetic Considerations
Ingår i Handbook of Experimental Pharmacology, 2020.
DOI för Brain Distribution of Drugs:: Pharmacokinetic Considerations
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In Vivo Studies of Drug BBB Transport:: Translational Challenges and the Role of Brain Imaging
Ingår i Handbook of Experimental Pharmacology, 2020.
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Mechanisms of a sustained anti-inflammatory drug response in alveolar macrophages unraveled with mathematical modeling
Ingår i CPT, s. 707-717, 2020.
DOI för Mechanisms of a sustained anti-inflammatory drug response in alveolar macrophages unraveled with mathematical modeling Ladda ner fulltext (pdf) av Mechanisms of a sustained anti-inflammatory drug response in alveolar macrophages unraveled with mathematical modeling
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Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis
Ingår i Archives of Toxicology, s. 2829-2845, 2020.
DOI för Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis Ladda ner fulltext (pdf) av Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis
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Perspectives on Nanodelivery to the Brain: Prerequisites for Successful Brain Treatment
Ingår i Molecular Pharmaceutics, s. 4029-4039, 2020.
DOI för Perspectives on Nanodelivery to the Brain: Prerequisites for Successful Brain Treatment Ladda ner fulltext (pdf) av Perspectives on Nanodelivery to the Brain: Prerequisites for Successful Brain Treatment
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A Cross-Sectional Study Assessing Appropriateness Of Inhaled Corticosteroid Treatment In Primary And Secondary Care Patients With COPD In Sweden
Ingår i The International Journal of Chronic Obstructive Pulmonary Disease, s. 2451-2460, 2019.
DOI för A Cross-Sectional Study Assessing Appropriateness Of Inhaled Corticosteroid Treatment In Primary And Secondary Care Patients With COPD In Sweden Ladda ner fulltext (pdf) av A Cross-Sectional Study Assessing Appropriateness Of Inhaled Corticosteroid Treatment In Primary And Secondary Care Patients With COPD In Sweden
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Amorphisation of Free Acid Ibuprofen and Other Profens in Mixtures with Nanocellulose: Dry Powder Formulation Strategy for Enhanced Solubility
Ingår i Pharmaceutics, 2019.
DOI för Amorphisation of Free Acid Ibuprofen and Other Profens in Mixtures with Nanocellulose: Dry Powder Formulation Strategy for Enhanced Solubility Ladda ner fulltext (pdf) av Amorphisation of Free Acid Ibuprofen and Other Profens in Mixtures with Nanocellulose: Dry Powder Formulation Strategy for Enhanced Solubility
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Building on the success of osimertinib: achieving CNS exposure in oncology drug discovery
Ingår i Drug Discovery Today, s. 1067-1073, 2019.
DOI för Building on the success of osimertinib: achieving CNS exposure in oncology drug discovery
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Computational modeling of lung deposition of inhaled particles in chronic obstructive pulmonary disease (COPD) patients: identification of gaps in knowledge and data
Ingår i Critical reviews in toxicology, s. 160-173, 2019.
DOI för Computational modeling of lung deposition of inhaled particles in chronic obstructive pulmonary disease (COPD) patients: identification of gaps in knowledge and data Ladda ner fulltext (pdf) av Computational modeling of lung deposition of inhaled particles in chronic obstructive pulmonary disease (COPD) patients: identification of gaps in knowledge and data
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Heterogeneous drug tissue binding in brain regions of rats, Alzheimer’s patients and controls: impact on translational drug development
Ingår i Scientific Reports, 2019.
DOI för Heterogeneous drug tissue binding in brain regions of rats, Alzheimer’s patients and controls: impact on translational drug development Ladda ner fulltext (pdf) av Heterogeneous drug tissue binding in brain regions of rats, Alzheimer’s patients and controls: impact on translational drug development
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Mechanistic Study on the Use of the L-Type Amino Acid Transporter 1 for Brain Intracellular Delivery of Ketoprofen via Prodrug: A Novel Approach Supporting the Development of Prodrugs for Intracellular Targets
Ingår i Molecular Pharmaceutics, s. 3261-3274, 2019.
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Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator
Ingår i EJNMMI Research, 2019.
DOI för Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator Ladda ner fulltext (pdf) av Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator
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Rate and extent of mitragynine and 7-hydroxymitragynine blood-brain barrier transport and their intra-brain distribution: the missing link in pharmacodynamic studies
Ingår i Addiction Biology, s. 935-945, 2019.
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Targeted Brain Delivery of Methotrexate by Glutathione PEGylated Liposomes: How can the Formulation Make a Difference?
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 197-204, 2019.
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Understanding the Influence of Nanocarrier-Mediated Brain Delivery on Therapeutic Performance Through Pharmacokinetic-Pharmacodynamic Modeling.
Ingår i Journal of Pharmaceutical Sciences, s. 3425-3433, 2019.
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Blood-Brain Barrier Integrity in a Mouse Model of Alzheimer’s Disease With or Without Acute 3D6 Immunotherapy
Ingår i Neuropharmacology, s. 1-9, 2018.
DOI för Blood-Brain Barrier Integrity in a Mouse Model of Alzheimer’s Disease With or Without Acute 3D6 Immunotherapy Ladda ner fulltext (pdf) av Blood-Brain Barrier Integrity in a Mouse Model of Alzheimer’s Disease With or Without Acute 3D6 Immunotherapy
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Intact blood-brain barrier transport of small molecular drugs in animal models of amyloid beta and alpha-synuclein pathology
Ingår i Neuropharmacology, s. 482-491, 2018.
DOI för Intact blood-brain barrier transport of small molecular drugs in animal models of amyloid beta and alpha-synuclein pathology Ladda ner fulltext (pdf) av Intact blood-brain barrier transport of small molecular drugs in animal models of amyloid beta and alpha-synuclein pathology
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Pharmacokinetics of Pericyte Involvement in Small-Molecular Drug Transport Across the Blood-Brain Barrier
Ingår i European Journal of Pharmaceutical Sciences, s. 77-84, 2018.
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Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Accurately Predicts the Better Bronchodilatory Effect of Inhaled Versus Oral Salbutamol Dosage Forms
Ingår i Journal of Aerosol Medicine, s. 1-12, 2018.
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Rate of Small-Molecular Drug Transport Across the Blood-Brain Barrier in a Pericyte-Deficient State
Ingår i European Journal of Pharmaceutical Sciences, s. 182-187, 2018.
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Uncovering the regional localization of inhaled salmeterol retention in the lung
Ingår i Drug Delivery, s. 838-845, 2018.
DOI för Uncovering the regional localization of inhaled salmeterol retention in the lung Ladda ner fulltext (pdf) av Uncovering the regional localization of inhaled salmeterol retention in the lung
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Benchmarking of Human Dose Prediction for Inhaled Medicines from Preclinical In Vivo Data
Ingår i Pharmaceutical research, s. 2557-2567, 2017.
DOI för Benchmarking of Human Dose Prediction for Inhaled Medicines from Preclinical In Vivo Data
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Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs
Ingår i Journal of Pharmaceutical Sciences, s. 2234-2244, 2017.
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Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017
Ingår i Fluids and Barriers of the CNS, 2017.
DOI för Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017 Ladda ner fulltext (pdf) av Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017
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Microdialysis as an Important Technique in Systems Pharmacology: a Historical and Methodological Review
Ingår i AAPS Journal, s. 1294-1303, 2017.
DOI för Microdialysis as an Important Technique in Systems Pharmacology: a Historical and Methodological Review Ladda ner fulltext (pdf) av Microdialysis as an Important Technique in Systems Pharmacology: a Historical and Methodological Review
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Professor Yuichi Sugiyama: A Brilliant, Creative, Amicable, Charming, and Humorous Pharmaceutical Scientist
Ingår i Journal of Pharmaceutical Sciences, s. 2188-2194, 2017.
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Quantitative Assessment of Drug Delivery to Tissues and Association with Phospholipidosis: A Case Study with Two Structurally Related Diamines in Development
Ingår i Molecular Pharmaceutics, s. 4362-4373, 2017.
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Recent advancements in liposomes targeting strategies to cross blood-brain barrier (BBB) for the treatment of Alzheimer's disease
Ingår i Journal of Controlled Release, s. 61-77, 2017.
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The Impact of Liposomal Formulations on the Release and Brain Delivery of Methotrexate: An In Vivo Microdialysis Study
Ingår i Journal of Pharmaceutical Sciences, s. 2606-2613, 2017.
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Development of a Novel Lung Slice Methodology for Profiling of Inhaled Compounds
Ingår i Journal of Pharmaceutical Sciences, s. 838-845, 2016.
DOI för Development of a Novel Lung Slice Methodology for Profiling of Inhaled Compounds
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Improved method for quantitative analysis of the cyclotide kalata B1 in plasma and brain homogenate
Ingår i Biopolymers, s. 910-916, 2016.
DOI för Improved method for quantitative analysis of the cyclotide kalata B1 in plasma and brain homogenate Ladda ner fulltext (pdf) av Improved method for quantitative analysis of the cyclotide kalata B1 in plasma and brain homogenate
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In vivo Functional Evaluation of Increased Brain Delivery of the Opioid Peptide DAMGO by Glutathione-PEGylated Liposomes
Ingår i Pharmaceutical research, s. 177-185, 2016.
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In-depth neuropharmacokinetic analysis of antipsychotics based on a novel approach to estimate unbound target-site concentration in CNS regions: link to spatial receptor occupancy
Ingår i Molecular Psychiatry, s. 1527-1536, 2016.