Publikationer 2016
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50 years of oral lipid-based formulations: Provenance, progress and future perspectives
Ingår i Advanced Drug Delivery Reviews, s. 167-194, 2016.
DOI för 50 years of oral lipid-based formulations: Provenance, progress and future perspectives
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A Tribute to Ronald T. Borchardt-Teacher, Mentor, Scientist, Colleague, Leader, Friend, and Family Man
Ingår i Journal of Pharmaceutical Sciences, s. 370-385, 2016.
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Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures
Ingår i ACS Chemical Neuroscience, s. 1383-1392, 2016.
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CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
Ingår i Nature Communications, 2016.
DOI för CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil Ladda ner fulltext (pdf) av CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
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Comparative proteome analysis of human liver tissue and isolated hepatocytes: application to predictions of hepatic pitavastatin uptake clearance
Ingår i Drug metabolism reviews (Softcover ed.), s. 96-96, 2016.
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Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9
Ingår i Journal of Pharmaceutical Sciences, s. 1017-1021, 2016.
DOI för Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9
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Compromised in vitro dissolution and membrane transport of multidrug amorphous formulations.
Ingår i Journal of Controlled Release, s. 172-182, 2016.
DOI för Compromised in vitro dissolution and membrane transport of multidrug amorphous formulations.
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Computational prediction of formulation strategies for beyond-rule-of-5 compounds
Ingår i Advanced Drug Delivery Reviews, s. 6-21, 2016.
DOI för Computational prediction of formulation strategies for beyond-rule-of-5 compounds Ladda ner fulltext (pdf) av Computational prediction of formulation strategies for beyond-rule-of-5 compounds
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Development of MS- based immunoassays for Cytochrome P450 and transporter quantification
Ingår i Naunyn-Schmiedeberg's Archives of Pharmacology, s. S47-S47, 2016.
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Diffusion-Controlled Drug Release from the Mesoporous Magnesium Carbonate Upsalite®
Ingår i Journal of Pharmaceutical Sciences, s. 657-663, 2016.
DOI för Diffusion-Controlled Drug Release from the Mesoporous Magnesium Carbonate Upsalite®
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Direct Measurement of Intracellular Compound Concentration by RapidFire Mass Spectrometry Offers Insights into Cell Permeability
Ingår i Journal of Biomolecular Screening, s. 156-164, 2016.
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Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1
Ingår i Journal of Medicinal Chemistry, s. 1140-1148, 2016.
DOI för Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1
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Global proteome changes in liver tissue 6 weeks after FOLFOX treatment of colorectal cancer liver metastases
Ingår i PROTEOMES, 2016.
DOI för Global proteome changes in liver tissue 6 weeks after FOLFOX treatment of colorectal cancer liver metastases Ladda ner fulltext (pdf) av Global proteome changes in liver tissue 6 weeks after FOLFOX treatment of colorectal cancer liver metastases
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Impact of drug transporters on intracellular unbound drug concentrations
Ingår i Drug metabolism reviews (Softcover ed.), s. 147-147, 2016.
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In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes
Ingår i Journal of Proteomics, s. 234-247, 2016.
DOI för In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes Ladda ner fulltext (pdf) av In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes
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Interlaboratory Validation of Small-Scale Solubility and Dissolution Measurements of Poorly Water-Soluble Drugs
Ingår i Journal of Pharmaceutical Sciences, s. 2864-2872, 2016.
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Lipophilicity in Drug Development: Too Much or Not Enough?
Ingår i AAPS Journal, s. 1095-1100, 2016.
DOI för Lipophilicity in Drug Development: Too Much or Not Enough?
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Mechanistic modeling of hepatic pitavastatin disposition: a proteomics-informed bottom-up approach
Ingår i Drug metabolism reviews (Softcover ed.), s. 56-57, 2016.
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Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach
Ingår i Drug Metabolism And Disposition, s. 505-516, 2016.
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New cell-based approaches for better predictions of drug transport and cellular drug exposure
Ingår i Drug metabolism reviews (Softcover ed.), s. 7-7, 2016.
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Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues
Ingår i Advanced Drug Delivery Reviews, s. 256-276, 2016.
DOI för Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues Ladda ner fulltext (pdf) av Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues
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Partitioning into Colloidal Structures of Fasted State Intestinal Fluid Studied by Molecular Dynamics Simulations
Ingår i Langmuir, s. 12732-12740, 2016.
DOI för Partitioning into Colloidal Structures of Fasted State Intestinal Fluid Studied by Molecular Dynamics Simulations Ladda ner fulltext (pdf) av Partitioning into Colloidal Structures of Fasted State Intestinal Fluid Studied by Molecular Dynamics Simulations
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Protein quantification of human hepatic drug transporters and metabolizing enzymes: an inter-laboratory and methodological comparison
Ingår i Drug metabolism reviews (Softcover ed.), s. 98-98, 2016.
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Rapid determination of drug solubilization versus supersaturation in natural and digested lipids
Ingår i International Journal of Pharmaceutics, s. 164-174, 2016.
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Structural and conformational determinants of macrocycle cell permeability
Ingår i Nature Chemical Biology, s. 1065-+, 2016.
DOI för Structural and conformational determinants of macrocycle cell permeability
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Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions
Ingår i Analytical Biochemistry, s. 82-88, 2016.
DOI för Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions Ladda ner fulltext (pdf) av Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions
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Supersaturation of poorly soluble drugs induced by mesoporous magnesium carbonate
Ingår i European Journal of Pharmaceutical Sciences, s. 468-474, 2016.
DOI för Supersaturation of poorly soluble drugs induced by mesoporous magnesium carbonate
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The Need for Speed-Kinetic Limits of Drug Transporters
Ingår i TIPS - Trends in Pharmacological Sciences, s. 243-245, 2016.
DOI för The Need for Speed-Kinetic Limits of Drug Transporters
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The Pro-inflammatory Cytokine Interleukin-6 Regulates Nanoparticle Transport Across Model Follicle-Associated Epithelium Cells
Ingår i Journal of Pharmaceutical Sciences, s. 2099-2104, 2016.
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The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition
Ingår i Journal of Pharmaceutical Sciences, s. 817-827, 2016.
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Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity
Ingår i Journal of Medicinal Chemistry, s. 2094-2108, 2016.
DOI för Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity
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To attach or not to attach: factors behind variable adhesion properties of cryopreserved human hepatocytes
Ingår i Drug metabolism reviews (Softcover ed.), s. 103-103, 2016.
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Tools for Early Prediction of Drug Loading in Lipid-Based Formulations
Ingår i Molecular Pharmaceutics, s. 251-261, 2016.
DOI för Tools for Early Prediction of Drug Loading in Lipid-Based Formulations
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Understanding the Challenge of Beyond-Rule-of-5 Compounds Preface
Ingår i Advanced Drug Delivery Reviews, s. 1-5, 2016.
DOI för Understanding the Challenge of Beyond-Rule-of-5 Compounds Preface