Publikationer från Bergström-gruppen

Early recognition of absorption challenges of contemporary targets:: key molecular properties and in silico tools

Bergström, Christel A S

Ingår i Bulletin Technique Gattefossé, s. 50-57, 2013.

Computational modeling to predict the functions and impact of drug transporters

Matsson, Pär; Bergström, Christel A S

Ingår i In silico pharmacology, 2015.

DOI för Computational modeling to predict the functions and impact of drug transporters Ladda ner fulltext (pdf) av Computational modeling to predict the functions and impact of drug transporters

Models for Predicting Drug Absorption From Oral Lipid-Based Formulations

Persson, Linda C.; Bergström, Christel A S

Ingår i Current molecular biology reports, s. 141-147, 2015.

DOI för Models for Predicting Drug Absorption From Oral Lipid-Based Formulations Ladda ner fulltext (pdf) av Models for Predicting Drug Absorption From Oral Lipid-Based Formulations

Intestinal solubility and absorption of poorly water soluble compounds: predictions, challenges and solutions

Fagerberg, Jonas H; Bergström, Christel A S

Ingår i Therapeutic delivery, s. 935-959, 2015.

DOI för Intestinal solubility and absorption of poorly water soluble compounds: predictions, challenges and solutions

Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability

Alhalaweh, Amjad; Alzghoul, Ahmad; Mahlin, Denny; Bergström, Christel A. S.

Ingår i International Journal of Pharmaceutics, s. 312-317, 2015.

DOI för Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability Ladda ner fulltext (pdf) av Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability

Experimental and Computational Prediction of Glass Transition Temperature of Drugs

Alzghoul, Ahmad; Alhalaweh, Amjad; Mahlin, Denny; Bergström, Christel A. S.

Ingår i JOURNAL OF CHEMICAL INFORMATION AND MODELING, s. 3396-3403, 2014.

DOI för Experimental and Computational Prediction of Glass Transition Temperature of Drugs

Formulation of the Microbicide INP0341 for In Vivo Protection against a Vaginal Challenge by Chlamydia trachomatis

Pedersen, Christian; Slepenkin, Anatoly; Andersson, Sara B. E.; Fagerberg, Jonas H. et al.

Ingår i PLOS ONE, s. e110918-, 2014.

DOI för Formulation of the Microbicide INP0341 for In Vivo Protection against a Vaginal Challenge by Chlamydia trachomatis Ladda ner fulltext (pdf) av Formulation of the Microbicide INP0341 for In Vivo Protection against a Vaginal Challenge by Chlamydia trachomatis

Pyridyl Benzamides as a Novel Class of Potent Inhibitors for the Kinetoplastid Trypanosoma brucei

Ferrins, Lori; Gazdik, Michelle; Rahmani, Raphael; Varghese, Swapna et al.

Ingår i Journal of Medicinal Chemistry, s. 6393-6402, 2014.

DOI för Pyridyl Benzamides as a Novel Class of Potent Inhibitors for the Kinetoplastid Trypanosoma brucei

Computational predictions of glass-forming ability and crystallization tendency of drug molecules

Alhalaweh, Amjad; Alzghoul, Ahmad; Kaialy, Waseem; Mahlin, Denny et al.

Ingår i Molecular Pharmaceutics, s. 3123-3132, 2014.

DOI för Computational predictions of glass-forming ability and crystallization tendency of drug molecules

Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs

Bergström, Christel A. S.; Holm, Rene; Jorgensen, Soren Astrup; Andersson, Sara B. E. et al.

Ingår i European Journal of Pharmaceutical Sciences, s. 173-199, 2014.

DOI för Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs

Is the full potential of the biopharmaceutics classification system reached?

Bergström, Christel A. S.; Andersson, Sara B. E.; Fagerberg, Jonas H.; Ragnarsson, Gert et al.

Ingår i European Journal of Pharmaceutical Sciences, s. 224-231, 2014.

DOI för Is the full potential of the biopharmaceutics classification system reached?

Computational Prediction of Drug Solubility in Fasted Simulated and Aspirated Human Intestinal Fluid

Fagerberg, Jonas H.; Karlsson, Eva; Ulander, Johan; Hanisch, Gunilla et al.

Ingår i Pharmaceutical research, s. 578-589, 2015.

DOI för Computational Prediction of Drug Solubility in Fasted Simulated and Aspirated Human Intestinal Fluid Ladda ner fulltext (pdf) av Computational Prediction of Drug Solubility in Fasted Simulated and Aspirated Human Intestinal Fluid

Concomitant intake of alcohol may increase the absorption of poorly soluble drugs

Fagerberg, Jonas H.; Sjögren, Erik; Bergström, Christel A. S.

Ingår i European Journal of Pharmaceutical Sciences, s. 12-20, 2015.

DOI för Concomitant intake of alcohol may increase the absorption of poorly soluble drugs Ladda ner fulltext (pdf) av Concomitant intake of alcohol may increase the absorption of poorly soluble drugs

Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients

Persson, Linda C.; Porter, Christopher J. H.; Charman, William N.; Bergström, Christel A. S.

Ingår i Pharmaceutical research, s. 3225-3237, 2013.

DOI för Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients Ladda ner fulltext (pdf) av Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients

Evaluation of the Structural Determinants of Polymeric Precipitation Inhibitors Using Solvent Shift Methods and Principle Component Analysis

Warren, Dallas B.; Bergström, Christel A. S.; Benameur, Hassan; Porter, Christopher J. H. et al.

Ingår i Molecular Pharmaceutics, s. 2823-2848, 2013.

DOI för Evaluation of the Structural Determinants of Polymeric Precipitation Inhibitors Using Solvent Shift Methods and Principle Component Analysis

Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11)

Pedersen, Jenny M.; Matsson, Pär; Bergström, Christel A. S.; Hoogstraate, Janet et al.

Ingår i Toxicological Sciences, s. 328-343, 2013.

DOI för Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11) Ladda ner fulltext (pdf) av Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11)

Early drug development predictions of glass-forming ability and physical stability of drugs

Mahlin, Denny; Bergström, Christel A. S.

Ingår i European Journal of Pharmaceutical Sciences, s. 323-332, 2013.

DOI för Early drug development predictions of glass-forming ability and physical stability of drugs Ladda ner fulltext (pdf) av Early drug development predictions of glass-forming ability and physical stability of drugs

Optimizing Solubility and Permeability of a Biopharmaceutics Classification System (BCS) Class 4 Antibiotic Drug Using Lipophilic Fragments Disturbing the Crystal Lattice

Tehler, Ulrika; Fagerberg, Jonas H.; Svensson, Richard; Larhed, Mats et al.

Ingår i Journal of Medicinal Chemistry, s. 2690-2694, 2013.

DOI för Optimizing Solubility and Permeability of a Biopharmaceutics Classification System (BCS) Class 4 Antibiotic Drug Using Lipophilic Fragments Disturbing the Crystal Lattice

Computational Prediction of CNS Drug Exposure Based on a Novel In Vivo Dataset

Bergstrom, Christel A. S.; Charman, Susan A.; Nicolazzo, Joseph A.

Ingår i Pharmaceutical research, s. 3131-3142, 2012.

DOI för Computational Prediction of CNS Drug Exposure Based on a Novel In Vivo Dataset

Ethanol Effects on Apparent Solubility of Poorly Soluble Drugs in Simulated Intestinal Fluid

Fagerberg, Jonas H.; Al-Tikriti, Yassir; Ragnarsson, Gert; Bergström, Christel A. S.

Ingår i Molecular Pharmaceutics, s. 1942-1952, 2012.

DOI för Ethanol Effects on Apparent Solubility of Poorly Soluble Drugs in Simulated Intestinal Fluid

Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Lazorova, Lucia; Hubatsch, Ina; Ekegren, Jenny K.; Gising, Johan et al.

Ingår i Journal of Pharmaceutical Sciences, s. 3763-3772, 2011.

DOI för Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Toward In Silico Prediction of Glass-Forming Ability from Molecular Structure Alone: A Screening Tool in Early Drug Development

Mahlin, Denny; Ponnambalam, Sopana; Hockerfelt, Mina Heidarian; Bergström, Christel A. S.

Ingår i Molecular Pharmaceutics, s. 498-506, 2011.

DOI för Toward In Silico Prediction of Glass-Forming Ability from Molecular Structure Alone: A Screening Tool in Early Drug Development

Interaction of 140 orally administered drugs with the liver-specific organic anion transporter OATP1B1 (SLCO1B1)

Karlgren, Maria; Ahlin, Gustav; Bergström, Christel; Karlsson, Johan et al.

Ingår i Drug metabolism reviews (Softcover ed.), s. 304-305, 2010.

Dissolution Rate and Apparent Solubility of Poorly Soluble Drugs in Biorelevant Dissolution Media

Fagerberg, Jonas H.; Tsinman, Oksana; Sun, Na; Tsinman, Konstantin et al.

Ingår i Molecular pharmaceutics, s. 1419-1430, 2010.

DOI för Dissolution Rate and Apparent Solubility of Poorly Soluble Drugs in Biorelevant Dissolution Media

A Modified Physiological BCS for Prediction of Intestinal Absorption in Drug Discovery

Zaki, Noha M.; Artursson, Per; Bergström, Christel A. S.

Ingår i Molecular pharmaceutics, s. 1478-1487, 2010.

DOI för A Modified Physiological BCS for Prediction of Intestinal Absorption in Drug Discovery

Hepatitis C virus NS3 protease inhibitors: large, flexible molecules of peptide origin show satisfactory permeability across Caco-2 cells

Bergström, Christel A S; Bolin, Sara; Artursson, Per; Rönn, Robert et al.

Ingår i European Journal of Pharmaceutical Sciences, s. 556-563, 2009.

DOI för Hepatitis C virus NS3 protease inhibitors: large, flexible molecules of peptide origin show satisfactory permeability across Caco-2 cells

Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs

Matsson, Pär; Pedersen, Jenny M; Norinder, Ulf; Bergström, Christel A S et al.

Ingår i Pharmaceutical research, s. 1816-1831, 2009.

DOI för Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs

In Vitro and In Silico Strategies to Identify OATP1B1 Inhibitors and Predict Clinical Drug-Drug Interactions

Karlgren, Maria; Ahlin, Gustav; Bergström, Christel A. S; Svensson, Richard et al.

Ingår i Pharmaceutical research, s. 411-426, 2012.

DOI för In Vitro and In Silico Strategies to Identify OATP1B1 Inhibitors and Predict Clinical Drug-Drug Interactions

Prediction of ADMET Properties

Norinder, Ulf; Bergström, Christel

Ingår i ChemMedChem, s. 920-937, 2006.

DOI för Prediction of ADMET Properties

Computational models to predict aqueous drug solubility, permeability and intestinal absorption

Bergström, Christel

Ingår i Expert opinion on drug metabolism & toxicology, s. 613-627, 2005.

DOI för Computational models to predict aqueous drug solubility, permeability and intestinal absorption

Theoretical predictions of drug absorption in drug discovery and development 

Stenberg, Patric; Bergström, Christel; Luthman, Kristina; Artursson, Per

Ingår i Clinical Pharmacokinetics, s. 877-899, 2002.

Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1

Ahlin, Gustav; Karlsson, Johan; Pedersen, Jenny M; Gustavsson, Lena et al.

Ingår i Journal of Medicinal Chemistry, s. 5932-5942, 2008.

DOI för Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1

Molecular characteristics for solid-state limited solubility

Wassvik, Carola M; Holmén, Anders G; Draheim, Rieke; Artursson, Per et al.

Ingår i Journal of Medicinal Chemistry, s. 3035-3039, 2008.

DOI för Molecular characteristics for solid-state limited solubility

Photoinduced Formation of N₂ Molecules in Ammonium Compounds

Aziz, Emad F; Gråsjö, Johan; Forsberg, Johan; Andersson, Egil et al.

Ingår i Journal of Physical Chemistry A, s. 9662-9669, 2007.

DOI för Photoinduced Formation of N₂ Molecules in Ammonium Compounds

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2)

Pedersen, Jenny; Matsson, Pär; Norinder, Ulf; Bergström, Christel A. S. et al.

Ingår i Journal of Medicinal Chemistry, s. 3275-3287, 2008.

DOI för Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2)

A Global Drug Inhibition Pattern for the Human ATP-Binding Cassette Transporter Breast Cancer Resistance Protein (ABCG2)

Matsson, Pär; Englund, Gunilla; Ahlin, Gustav; Bergström, Christel A. S. et al.

Ingår i Journal of Pharmacology and Experimental Therapeutics, s. 19-30, 2007.

DOI för A Global Drug Inhibition Pattern for the Human ATP-Binding Cassette Transporter Breast Cancer Resistance Protein (ABCG2)

Poorly soluble marketed drugs display solvation limited solubility

Bergström, Christel; Wassvik, Carola M.; Johansson, Kajsa; Hubatsch, Ina

Ingår i Journal of Medicinal Chemistry, s. 5858-5862, 2007.

DOI för Poorly soluble marketed drugs display solvation limited solubility

X-ray yield and selectively excited X-ray emission spectra of atenolol and nadolol.

Söderström, Johan; Gråsjö, Johan; Kashtanov, S; Bergström, Christel et al.

Ingår i J Electr Spectr, s. 283-285, 2005.

Contribution of solid-state properties to the aqueous solubility of drugs.

Wassvik, Carola; Holmén, Anders; Bergström, Christel; Zamora, Ismael et al.

Ingår i Eur J Pharm Sci, s. 294-305, 2006.

Prediction of ADMET Properties.

Norinder, U; Bergström, C

Ingår i ChemMedChem, s. 920-937, 2006.