Publikationer från Bergström-gruppen
Publikationer
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Magnetoresponsive fluorescent core-shell nanoclusters for biomedical applications
Ingår i Nanoscale Advances, s. 1323-1330, 2023.
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DOI för Magnetoresponsive fluorescent core-shell nanoclusters for biomedical applications Ladda ner fulltext (pdf) av Magnetoresponsive fluorescent core-shell nanoclusters for biomedical applications
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Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer
Ingår i International Journal of Biological Macromolecules, 2023.
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Pickering emulsion gel enables 3D printing of lipid-rich solid oral dosage forms
Artikel i tidskrift
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Development and validation of a porcine artificial colonic mucus model reflecting the properties of native colonic mucus in pigs
Ingår i European Journal of Pharmaceutical Sciences, 2023.
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DOI för Development and validation of a porcine artificial colonic mucus model reflecting the properties of native colonic mucus in pigs Ladda ner fulltext (pdf) av Development and validation of a porcine artificial colonic mucus model reflecting the properties of native colonic mucus in pigs
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Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin
Ingår i Molecular Pharmaceutics, s. 3922-3933, 2022.
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DOI för Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin Ladda ner fulltext (pdf) av Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin
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Inorganic nanoparticles for oral drug delivery: opportunities, barriers, and future perspectives
Ingår i Current Opinion in Chemical Engineering, 2022.
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DOI för Inorganic nanoparticles for oral drug delivery: opportunities, barriers, and future perspectives Ladda ner fulltext (pdf) av Inorganic nanoparticles for oral drug delivery: opportunities, barriers, and future perspectives
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Intrinsic lipolysis rate for systematic design of lipid-based formulations
Ingår i Drug Delivery and Translational Research, 2022.
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DOI för Intrinsic lipolysis rate for systematic design of lipid-based formulations Ladda ner fulltext (pdf) av Intrinsic lipolysis rate for systematic design of lipid-based formulations
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Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers
Ingår i International Journal of Pharmaceutics, 2022.
Artikel i tidskrift
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Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs
Ingår i Molecular Pharmaceutics, s. 451-460, 2023.
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DOI för Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs Ladda ner fulltext (pdf) av Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs
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Bioavailability of Celecoxib Formulated with Mesoporous Magnesium Carbonate: An In Vivo Evaluation
Ingår i Molecules, 2022.
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DOI för Bioavailability of Celecoxib Formulated with Mesoporous Magnesium Carbonate: An In Vivo Evaluation Ladda ner fulltext (pdf) av Bioavailability of Celecoxib Formulated with Mesoporous Magnesium Carbonate: An In Vivo Evaluation
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Membrane insertion mechanism of the caveola coat protein Cavin1
Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2022.
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DOI för Membrane insertion mechanism of the caveola coat protein Cavin1 Ladda ner fulltext (pdf) av Membrane insertion mechanism of the caveola coat protein Cavin1
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Intestinal Absorption of FITC-Dextrans and Macromolecular Model Drugs in the Rat Intestinal Instillation Model
Ingår i Molecular Pharmaceutics, s. 2564-2572, 2022.
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DOI för Intestinal Absorption of FITC-Dextrans and Macromolecular Model Drugs in the Rat Intestinal Instillation Model Ladda ner fulltext (pdf) av Intestinal Absorption of FITC-Dextrans and Macromolecular Model Drugs in the Rat Intestinal Instillation Model
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Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms
Ingår i ACS Applied Materials and Interfaces, s. 21978-21988, 2022.
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DOI för Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms Ladda ner fulltext (pdf) av Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms
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Gastrointestinal mucus in dog: Physiological characteristics, composition, and structural properties
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 92-102, 2022.
Artikel i tidskrift
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Aggregation Behavior of Structurally Similar Therapeutic Peptides Investigated by H-1 NMR and All-Atom Molecular Dynamics Simulations
Ingår i Molecular Pharmaceutics, s. 904-917, 2022.
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DOI för Aggregation Behavior of Structurally Similar Therapeutic Peptides Investigated by H-1 NMR and All-Atom Molecular Dynamics Simulations Ladda ner fulltext (pdf) av Aggregation Behavior of Structurally Similar Therapeutic Peptides Investigated by H-1 NMR and All-Atom Molecular Dynamics Simulations
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Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat
Ingår i Molecular Pharmaceutics, s. 200-212, 2022.
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DOI för Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat Ladda ner fulltext (pdf) av Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat
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Manipulations and age-appropriateness of oral medications in pediatric oncology patients in Sweden: Need for personalized dosage forms
Ingår i Biomedicine and Pharmacotherapy, s. 112576-112576, 2022.
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DOI för Manipulations and age-appropriateness of oral medications in pediatric oncology patients in Sweden: Need for personalized dosage forms Ladda ner fulltext (pdf) av Manipulations and age-appropriateness of oral medications in pediatric oncology patients in Sweden: Need for personalized dosage forms
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Explicit-pH Coarse-Grained Molecular Dynamics Simulations Enable Insights into Restructuring of Intestinal Colloidal Aggregates with Permeation Enhancers
Ingår i Processes, s. 29-, 2022.
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DOI för Explicit-pH Coarse-Grained Molecular Dynamics Simulations Enable Insights into Restructuring of Intestinal Colloidal Aggregates with Permeation Enhancers Ladda ner fulltext (pdf) av Explicit-pH Coarse-Grained Molecular Dynamics Simulations Enable Insights into Restructuring of Intestinal Colloidal Aggregates with Permeation Enhancers
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In Silico-Based Experiments on Mechanistic Interactions between Several Intestinal Permeation Enhancers with a Lipid Bilayer Model
Ingår i Molecular Pharmaceutics, s. 124-137, 2022.
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DOI för In Silico-Based Experiments on Mechanistic Interactions between Several Intestinal Permeation Enhancers with a Lipid Bilayer Model Ladda ner fulltext (pdf) av In Silico-Based Experiments on Mechanistic Interactions between Several Intestinal Permeation Enhancers with a Lipid Bilayer Model
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Sustainability in drug discovery
Ingår i Medicine in Drug Discovery, 2021.
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DOI för Sustainability in drug discovery Ladda ner fulltext (pdf) av Sustainability in drug discovery
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Pharmaceutical Profiling and Molecular Dynamics Simulations Reveal Crystallization Effects in Amorphous Formulations
Ingår i International Journal of Pharmaceutics, 2021.
Artikel i tidskrift
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Celebrating Women in the Pharmaceutical Sciences
Ingår i Molecular Pharmaceutics, s. 1487-1490, 2021.
Artikel i tidskrift
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UNGAP best practice for improving solubility data quality of orally administered drugs
Ingår i European Journal of Pharmaceutical Sciences, 2022.
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DOI för UNGAP best practice for improving solubility data quality of orally administered drugs Ladda ner fulltext (pdf) av UNGAP best practice for improving solubility data quality of orally administered drugs
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Impact of Simulated Intestinal Fluids on Dissolution, Solution Chemistry, and Membrane Transport of Amorphous Multidrug Formulations
Ingår i Molecular Pharmaceutics, s. 4079-4089, 2021.
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DOI för Impact of Simulated Intestinal Fluids on Dissolution, Solution Chemistry, and Membrane Transport of Amorphous Multidrug Formulations Ladda ner fulltext (pdf) av Impact of Simulated Intestinal Fluids on Dissolution, Solution Chemistry, and Membrane Transport of Amorphous Multidrug Formulations
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Increasing the Transport of Celecoxib over a Simulated Intestine Cell Membrane Model Using Mesoporous Magnesium Carbonate
Ingår i Molecules, 2021.
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DOI för Increasing the Transport of Celecoxib over a Simulated Intestine Cell Membrane Model Using Mesoporous Magnesium Carbonate Ladda ner fulltext (pdf) av Increasing the Transport of Celecoxib over a Simulated Intestine Cell Membrane Model Using Mesoporous Magnesium Carbonate
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Physiological properties, composition and structural profiling of porcine gastrointestinal mucus
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 156-167, 2021.
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DOI för Physiological properties, composition and structural profiling of porcine gastrointestinal mucus Ladda ner fulltext (pdf) av Physiological properties, composition and structural profiling of porcine gastrointestinal mucus
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Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa
Ingår i ACS INFECTIOUS DISEASES, s. 2666-2685, 2021.
Artikel i tidskrift
DOI för Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa Ladda ner fulltext (pdf) av Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa
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Comparison of cellular monolayers and an artificial membrane as absorptive membranes in the in vitro lipolysis-permeation assay
Ingår i Journal of Pharmaceutical Sciences, s. 175-184, 2022.
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DOI för Comparison of cellular monolayers and an artificial membrane as absorptive membranes in the in vitro lipolysis-permeation assay Ladda ner fulltext (pdf) av Comparison of cellular monolayers and an artificial membrane as absorptive membranes in the in vitro lipolysis-permeation assay
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Investigation of Self-Emulsifying Drug-Delivery System Interaction with a Biomimetic Membrane under Conditions Relevant to the Small Intestine
Ingår i Langmuir, s. 10200-10213, 2021.
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DOI för Investigation of Self-Emulsifying Drug-Delivery System Interaction with a Biomimetic Membrane under Conditions Relevant to the Small Intestine Ladda ner fulltext (pdf) av Investigation of Self-Emulsifying Drug-Delivery System Interaction with a Biomimetic Membrane under Conditions Relevant to the Small Intestine
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The Effect of the Molecular Weight of Polyvinylpyrrolidone and the Model Drug on Laser-Induced In Situ Amorphization
Ingår i Molecules, 2021.
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DOI för The Effect of the Molecular Weight of Polyvinylpyrrolidone and the Model Drug on Laser-Induced In Situ Amorphization Ladda ner fulltext (pdf) av The Effect of the Molecular Weight of Polyvinylpyrrolidone and the Model Drug on Laser-Induced In Situ Amorphization
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Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet
Ingår i Molecular Pharmaceutics, s. 2254-2262, 2021.
Artikel i tidskrift
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The Influence of Drug-Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles
Ingår i Pharmaceutics, 2021.
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DOI för The Influence of Drug-Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles Ladda ner fulltext (pdf) av The Influence of Drug-Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles
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3D-printing of solid lipid tablets from emulsion gels
Ingår i International Journal of Pharmaceutics, 2021.
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DOI för 3D-printing of solid lipid tablets from emulsion gels Ladda ner fulltext (pdf) av 3D-printing of solid lipid tablets from emulsion gels
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Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease
Ingår i Journal of Pharmaceutical Sciences, s. 239-250, 2021.
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DOI för Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease Ladda ner fulltext (pdf) av Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease
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Synergistic Computational Modeling Approaches as Team Players in the Game of Solubility Predictions
Ingår i Journal of Pharmaceutical Sciences, s. 22-34, 2021.
Artikel i tidskrift
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A Tribute to Professor Per Artursson - Scientist, Explorer, Mentor, Innovator, and Giant in Pharmaceutical Research
Ingår i Journal of Pharmaceutical Sciences, s. 2-11, 2021.
Artikel i tidskrift
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In Vitro and In Vivo Evaluation of 3D Printed Capsules with Pressure Triggered Release Mechanism for Oral Peptide Delivery
Ingår i Journal of Pharmaceutical Sciences, s. 228-238, 2021.
Artikel i tidskrift
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Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation
Ingår i Journal of Pharmaceutical Sciences, s. 176-185, 2021.
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DOI för Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation Ladda ner fulltext (pdf) av Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation
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Model-Informed Drug Discovery and Development in Pulmonary Delivery: Biopharmaceutical Pharmacometric Modeling for Formulation Evaluation of Pulmonary Suspensions
Ingår i ACS Omega, s. 25733-25746, 2020.
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DOI för Model-Informed Drug Discovery and Development in Pulmonary Delivery: Biopharmaceutical Pharmacometric Modeling for Formulation Evaluation of Pulmonary Suspensions Ladda ner fulltext (pdf) av Model-Informed Drug Discovery and Development in Pulmonary Delivery: Biopharmaceutical Pharmacometric Modeling for Formulation Evaluation of Pulmonary Suspensions
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Strategies of solubility enhancement and perspectives in solubility measurements of pharmaceutical compounds
Ingår i ADMET & DMPK, s. 176-179, 2020.
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DOI för Strategies of solubility enhancement and perspectives in solubility measurements of pharmaceutical compounds Ladda ner fulltext (pdf) av Strategies of solubility enhancement and perspectives in solubility measurements of pharmaceutical compounds
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A comparison of chitosan, mesoporous silica and poly(lactic-co-glycolic) acid nanocarriers for optimising intestinal uptake of oral protein therapeutics
Ingår i Journal of Pharmaceutical Sciences, s. 217-227, 2021.
Artikel i tidskrift
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Contemporary formulation development for inhaled pharmaceuticals
Ingår i Journal of Pharmaceutical Sciences, s. 66-86, 2021.
Artikel, forskningsöversikt
DOI för Contemporary formulation development for inhaled pharmaceuticals Ladda ner fulltext (pdf) av Contemporary formulation development for inhaled pharmaceuticals
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TIRF Microscopy‐Based Monitoring of Drug Permeation Across a Lipid Membrane Supported on Mesoporous Silica
Ingår i Angewandte Chemie International Edition, s. 2069-2073, 2021.
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DOI för TIRF Microscopy‐Based Monitoring of Drug Permeation Across a Lipid Membrane Supported on Mesoporous Silica Ladda ner fulltext (pdf) av TIRF Microscopy‐Based Monitoring of Drug Permeation Across a Lipid Membrane Supported on Mesoporous Silica
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Insights into Dissolution and Solution Chemistry of Multidrug Formulations of Antihypertensive Drugs
Ingår i Molecular Pharmaceutics, s. 4018-4028, 2020.
Artikel i tidskrift
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Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers
Ingår i Molecular Pharmaceutics, s. 4226-4240, 2020.
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DOI för Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers Ladda ner fulltext (pdf) av Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers
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Molecular Dynamics Simulations on Interindividual Variability of Intestinal Fluids: Impact on Drug Solubilization
Ingår i Molecular Pharmaceutics, s. 3837-3844, 2020.
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DOI för Molecular Dynamics Simulations on Interindividual Variability of Intestinal Fluids: Impact on Drug Solubilization Ladda ner fulltext (pdf) av Molecular Dynamics Simulations on Interindividual Variability of Intestinal Fluids: Impact on Drug Solubilization
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Automated assays for thermodynamic (equilibrium) solubility determination.
Ingår i Drug Discovery Today, s. 11-19, 2018.
Artikel i tidskrift
DOI för Automated assays for thermodynamic (equilibrium) solubility determination.
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Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media
Ingår i Pharmaceutics, 2020.
Artikel i tidskrift
DOI för Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media Ladda ner fulltext (pdf) av Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media
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MkVsites: A tool for creating GROMACS virtual sites parameters to increase performance in all-atom molecular dynamics simulations.
Ingår i Journal of Computational Chemistry, s. 1564-1569, 2020.
Artikel i tidskrift
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Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa
Ingår i Frontiers in Chemistry, 2020.
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DOI för Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa Ladda ner fulltext (pdf) av Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa
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Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions
Ingår i Pharmaceutics, 2020.
Artikel i tidskrift
DOI för Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions Ladda ner fulltext (pdf) av Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions
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In Vitro Performance and Chemical Stability of Lipid-Based Formulations Encapsulated in a Mesoporous Magnesium Carbonate Carrier
Ingår i Pharmaceutics, 2020.
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DOI för In Vitro Performance and Chemical Stability of Lipid-Based Formulations Encapsulated in a Mesoporous Magnesium Carbonate Carrier Ladda ner fulltext (pdf) av In Vitro Performance and Chemical Stability of Lipid-Based Formulations Encapsulated in a Mesoporous Magnesium Carbonate Carrier
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Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic-Pharmacodynamic Modeling for Evaluation of Treatments against Chronic Pseudomonas aeruginosa Lung Infections
Ingår i Molecular Pharmaceutics, s. 1458-1469, 2020.
Artikel i tidskrift
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An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 21-29, 2020.
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DOI för An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems Ladda ner fulltext (pdf) av An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems
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Suitability of Artificial Membranes in Lipolysis-Permeation Assays of Oral Lipid-Based Formulations
Ingår i Pharmaceutical research, 2020.
Artikel i tidskrift
DOI för Suitability of Artificial Membranes in Lipolysis-Permeation Assays of Oral Lipid-Based Formulations Ladda ner fulltext (pdf) av Suitability of Artificial Membranes in Lipolysis-Permeation Assays of Oral Lipid-Based Formulations
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Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties
Ingår i AAPS Journal, 2020.
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DOI för Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties Ladda ner fulltext (pdf) av Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties
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The Permeation of Acamprosate Is Predominantly Caused by Paracellular Diffusion across Caco-2 Cell Monolayers: A Paracellular Modeling Approach
Ingår i Molecular Pharmaceutics, s. 4636-4650, 2019.
Artikel i tidskrift
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Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems
Ingår i European Journal of Pharmaceutical Sciences, 2019.
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DOI för Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems Ladda ner fulltext (pdf) av Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems
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Does the Intake of Ethanol Affect Oral Absorption of Poorly Soluble Drugs?
Ingår i Journal of Pharmaceutical Sciences, s. 1765-1771, 2019.
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DOI för Does the Intake of Ethanol Affect Oral Absorption of Poorly Soluble Drugs? Ladda ner fulltext (pdf) av Does the Intake of Ethanol Affect Oral Absorption of Poorly Soluble Drugs?
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The Biopharmaceutics Classification System (BCS) and the Biopharmaceutics Drug Disposition Classification System (BDDCS): Beyond guidelines
Ingår i International Journal of Pharmaceutics, s. 264-281, 2019.
Artikel, forskningsöversikt
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Long-term physical (in)stability of spray-dried amorphous drugs: relationship with glass-forming ability and physicochemical properties
Ingår i Pharmaceutics, 2019.
Artikel i tidskrift
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Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage
Ingår i Molecules, 2019.
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DOI för Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage Ladda ner fulltext (pdf) av Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage
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Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 101-114, 2019.
Artikel, forskningsöversikt
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Perspectives in solubility measurement and interpretation
Ingår i ADMET AND DMPK, s. 88-105, 2019.
Artikel, forskningsöversikt
DOI för Perspectives in solubility measurement and interpretation Ladda ner fulltext (pdf) av Perspectives in solubility measurement and interpretation
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Molecular simulation as a computational pharmaceutics tool to predict drug solubility, solubilization processes and partitioning
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 46-55, 2019.
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DOI för Molecular simulation as a computational pharmaceutics tool to predict drug solubility, solubilization processes and partitioning Ladda ner fulltext (pdf) av Molecular simulation as a computational pharmaceutics tool to predict drug solubility, solubilization processes and partitioning
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Lipolysis-Permeation Setup for Simultaneous Study of Digestion and Absorption in Vitro
Ingår i Molecular Pharmaceutics, s. 921-930, 2019.
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DOI för Lipolysis-Permeation Setup for Simultaneous Study of Digestion and Absorption in Vitro Ladda ner fulltext (pdf) av Lipolysis-Permeation Setup for Simultaneous Study of Digestion and Absorption in Vitro
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Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection
Ingår i Journal of Pharmaceutical Sciences, s. 630-640, 2019.
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DOI för Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection Ladda ner fulltext (pdf) av Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection
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Molecular Drivers of Crystallization Kinetics for Drugs in Supersaturated Aqueous Solutions
Ingår i Journal of Pharmaceutical Sciences, s. 252-259, 2019.
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DOI för Molecular Drivers of Crystallization Kinetics for Drugs in Supersaturated Aqueous Solutions Ladda ner fulltext (pdf) av Molecular Drivers of Crystallization Kinetics for Drugs in Supersaturated Aqueous Solutions
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Fifty-Eight Years and Counting: High-Impact Publishing in Computational Pharmaceutical Sciences and Mechanism-Based Modeling
Ingår i Journal of Pharmaceutical Sciences, s. 2-7, 2019.
Artikel i tidskrift
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Aggregation Behavior of Medium Chain Fatty Acids Studied by Coarse-Grained Molecular Dynamics Simulation
Ingår i AAPS PharmSciTech, 2019.
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DOI för Aggregation Behavior of Medium Chain Fatty Acids Studied by Coarse-Grained Molecular Dynamics Simulation Ladda ner fulltext (pdf) av Aggregation Behavior of Medium Chain Fatty Acids Studied by Coarse-Grained Molecular Dynamics Simulation
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Effect of lipids on absorption of carvedilol in dogs: Is coadministration of lipids as efficient as a lipid-based formulation?
Ingår i Journal of Controlled Release, s. 90-100, 2019.
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DOI för Effect of lipids on absorption of carvedilol in dogs: Is coadministration of lipids as efficient as a lipid-based formulation? Ladda ner fulltext (pdf) av Effect of lipids on absorption of carvedilol in dogs: Is coadministration of lipids as efficient as a lipid-based formulation?
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Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations
Ingår i Molecular Pharmaceutics, s. 4733-4744, 2018.
Artikel i tidskrift
DOI för Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations Ladda ner fulltext (pdf) av Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations
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In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance
Ingår i AAPS Journal, 2018.
Artikel i tidskrift
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Emulsions Stabilized by Chitosan-Modified Silica Nanoparticles: pH Control of Structure-Property Relations
Ingår i Langmuir, s. 6147-6160, 2018.
Artikel i tidskrift
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A Modified In Situ Method to Determine Release from a Complex Drug Carrier in Particle-Rich Suspensions
Ingår i AAPS PharmSciTech, s. 2859-2865, 2018.
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DOI för A Modified In Situ Method to Determine Release from a Complex Drug Carrier in Particle-Rich Suspensions Ladda ner fulltext (pdf) av A Modified In Situ Method to Determine Release from a Complex Drug Carrier in Particle-Rich Suspensions
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Amorphous Magnesium Carbonate Nanoparticles with Strong Stabilizing Capability for Amorphous Ibuprofen
Ingår i International Journal of Pharmaceutics, s. 515-521, 2018.
Artikel i tidskrift
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Computational prediction of drug solubility in water-based systems: qualitative and quantitative approaches used in the current drug discovery and development setting
Ingår i International Journal of Pharmaceutics, s. 185-193, 2018.
Artikel, forskningsöversikt
DOI för Computational prediction of drug solubility in water-based systems: qualitative and quantitative approaches used in the current drug discovery and development setting Ladda ner fulltext (pdf) av Computational prediction of drug solubility in water-based systems: qualitative and quantitative approaches used in the current drug discovery and development setting
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Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations
Ingår i Pharmaceutical research, 2018.
Artikel i tidskrift
DOI för Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations Ladda ner fulltext (pdf) av Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations
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The Need for Restructuring the Disordered Science of Amorphous Drug Formulations
Ingår i Pharmaceutical Research, s. 1754-1772, 2017.
Artikel, forskningsöversikt
DOI för The Need for Restructuring the Disordered Science of Amorphous Drug Formulations Ladda ner fulltext (pdf) av The Need for Restructuring the Disordered Science of Amorphous Drug Formulations
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Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid
Ingår i Journal of Physical Chemistry B, s. 10869-10881, 2017.
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DOI för Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid Ladda ner fulltext (pdf) av Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid
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Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method
Ingår i Molecular Pharmaceutics, s. 4161-4169, 2017.
Artikel i tidskrift
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Controlled Suspensions Enable Rapid Determinations of Intrinsic Dissolution Rate and Apparent Solubility of Poorly Water-Soluble Compounds
Ingår i Pharmaceutical research, s. 1805-1816, 2017.
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DOI för Controlled Suspensions Enable Rapid Determinations of Intrinsic Dissolution Rate and Apparent Solubility of Poorly Water-Soluble Compounds Ladda ner fulltext (pdf) av Controlled Suspensions Enable Rapid Determinations of Intrinsic Dissolution Rate and Apparent Solubility of Poorly Water-Soluble Compounds
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Molecular Structuring and Phase Transition of Lipid-Based Formulations upon Water Dispersion: A Coarse-Grained Molecular Dynamics Simulation Approach
Ingår i Molecular Pharmaceutics, s. 4145-4153, 2017.
Artikel i tidskrift
DOI för Molecular Structuring and Phase Transition of Lipid-Based Formulations upon Water Dispersion: A Coarse-Grained Molecular Dynamics Simulation Approach Ladda ner fulltext (pdf) av Molecular Structuring and Phase Transition of Lipid-Based Formulations upon Water Dispersion: A Coarse-Grained Molecular Dynamics Simulation Approach
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Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways
Ingår i Journal of Controlled Release, s. 193-202, 2017.
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DOI för Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways Ladda ner fulltext (pdf) av Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways
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Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2)
Ingår i European Journal of Pharmaceutical Sciences, s. 70-76, 2017.
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DOI för Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2)
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Enhanced release of poorly water-soluble drugs from synergy between mesoporous magnesium carbonate and polymers
Ingår i International Journal of Pharmaceutics, s. 183-190, 2017.
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Partitioning into Colloidal Structures of Fasted State Intestinal Fluid Studied by Molecular Dynamics Simulations
Ingår i Langmuir, s. 12732-12740, 2016.
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DOI för Partitioning into Colloidal Structures of Fasted State Intestinal Fluid Studied by Molecular Dynamics Simulations Ladda ner fulltext (pdf) av Partitioning into Colloidal Structures of Fasted State Intestinal Fluid Studied by Molecular Dynamics Simulations
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Rapid determination of drug solubilization versus supersaturation in natural and digested lipids
Ingår i International Journal of Pharmaceutics, s. 164-174, 2016.
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Lipophilicity in Drug Development: Too Much or Not Enough?
Ingår i AAPS Journal, s. 1095-1100, 2016.
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DOI för Lipophilicity in Drug Development: Too Much or Not Enough?
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Supersaturation of poorly soluble drugs induced by mesoporous magnesium carbonate
Ingår i European Journal of Pharmaceutical Sciences, s. 468-474, 2016.
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DOI för Supersaturation of poorly soluble drugs induced by mesoporous magnesium carbonate
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Understanding the Challenge of Beyond-Rule-of-5 Compounds Preface
Ingår i Advanced Drug Delivery Reviews, s. 1-5, 2016.
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DOI för Understanding the Challenge of Beyond-Rule-of-5 Compounds Preface
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50 years of oral lipid-based formulations: Provenance, progress and future perspectives
Ingår i Advanced Drug Delivery Reviews, s. 167-194, 2016.
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DOI för 50 years of oral lipid-based formulations: Provenance, progress and future perspectives
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Interlaboratory Validation of Small-Scale Solubility and Dissolution Measurements of Poorly Water-Soluble Drugs
Ingår i Journal of Pharmaceutical Sciences, s. 2864-2872, 2016.
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Computational prediction of formulation strategies for beyond-rule-of-5 compounds
Ingår i Advanced Drug Delivery Reviews, s. 6-21, 2016.
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DOI för Computational prediction of formulation strategies for beyond-rule-of-5 compounds Ladda ner fulltext (pdf) av Computational prediction of formulation strategies for beyond-rule-of-5 compounds
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Compromised in vitro dissolution and membrane transport of multidrug amorphous formulations.
Ingår i Journal of Controlled Release, s. 172-182, 2016.
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DOI för Compromised in vitro dissolution and membrane transport of multidrug amorphous formulations.
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Early recognition of absorption challenges of contemporary targets:: key molecular properties and in silico tools
Ingår i Bulletin Technique Gattefossé, s. 50-57, 2013.
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Computational modeling to predict the functions and impact of drug transporters
Ingår i In silico pharmacology, 2015.
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DOI för Computational modeling to predict the functions and impact of drug transporters Ladda ner fulltext (pdf) av Computational modeling to predict the functions and impact of drug transporters
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Models for Predicting Drug Absorption From Oral Lipid-Based Formulations
Ingår i Current molecular biology reports, s. 141-147, 2015.
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DOI för Models for Predicting Drug Absorption From Oral Lipid-Based Formulations Ladda ner fulltext (pdf) av Models for Predicting Drug Absorption From Oral Lipid-Based Formulations
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Intestinal solubility and absorption of poorly water soluble compounds: predictions, challenges and solutions
Ingår i Therapeutic delivery, s. 935-959, 2015.
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Tools for Early Prediction of Drug Loading in Lipid-Based Formulations
Ingår i Molecular Pharmaceutics, s. 251-261, 2016.
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DOI för Tools for Early Prediction of Drug Loading in Lipid-Based Formulations
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Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability
Ingår i International Journal of Pharmaceutics, s. 312-317, 2015.
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DOI för Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability Ladda ner fulltext (pdf) av Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability
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Diffusion-Controlled Drug Release from the Mesoporous Magnesium Carbonate Upsalite®
Ingår i Journal of Pharmaceutical Sciences, s. 657-663, 2016.
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DOI för Diffusion-Controlled Drug Release from the Mesoporous Magnesium Carbonate Upsalite®
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Experimental and Computational Prediction of Glass Transition Temperature of Drugs
Ingår i JOURNAL OF CHEMICAL INFORMATION AND MODELING, s. 3396-3403, 2014.
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DOI för Experimental and Computational Prediction of Glass Transition Temperature of Drugs
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Formulation of the Microbicide INP0341 for In Vivo Protection against a Vaginal Challenge by Chlamydia trachomatis
Ingår i PLOS ONE, s. e110918-, 2014.
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DOI för Formulation of the Microbicide INP0341 for In Vivo Protection against a Vaginal Challenge by Chlamydia trachomatis Ladda ner fulltext (pdf) av Formulation of the Microbicide INP0341 for In Vivo Protection against a Vaginal Challenge by Chlamydia trachomatis
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Pyridyl Benzamides as a Novel Class of Potent Inhibitors for the Kinetoplastid Trypanosoma brucei
Ingår i Journal of Medicinal Chemistry, s. 6393-6402, 2014.
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Computational predictions of glass-forming ability and crystallization tendency of drug molecules
Ingår i Molecular Pharmaceutics, s. 3123-3132, 2014.
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Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs
Ingår i European Journal of Pharmaceutical Sciences, s. 173-199, 2014.
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Is the full potential of the biopharmaceutics classification system reached?
Ingår i European Journal of Pharmaceutical Sciences, s. 224-231, 2014.
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DOI för Is the full potential of the biopharmaceutics classification system reached?
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Computational Prediction of Drug Solubility in Fasted Simulated and Aspirated Human Intestinal Fluid
Ingår i Pharmaceutical research, s. 578-589, 2015.
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DOI för Computational Prediction of Drug Solubility in Fasted Simulated and Aspirated Human Intestinal Fluid Ladda ner fulltext (pdf) av Computational Prediction of Drug Solubility in Fasted Simulated and Aspirated Human Intestinal Fluid
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Concomitant intake of alcohol may increase the absorption of poorly soluble drugs
Ingår i European Journal of Pharmaceutical Sciences, s. 12-20, 2015.
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DOI för Concomitant intake of alcohol may increase the absorption of poorly soluble drugs Ladda ner fulltext (pdf) av Concomitant intake of alcohol may increase the absorption of poorly soluble drugs
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Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients
Ingår i Pharmaceutical research, s. 3225-3237, 2013.
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DOI för Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients Ladda ner fulltext (pdf) av Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients
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Evaluation of the Structural Determinants of Polymeric Precipitation Inhibitors Using Solvent Shift Methods and Principle Component Analysis
Ingår i Molecular Pharmaceutics, s. 2823-2848, 2013.
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Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11)
Ingår i Toxicological Sciences, s. 328-343, 2013.
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DOI för Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11) Ladda ner fulltext (pdf) av Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11)
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Early drug development predictions of glass-forming ability and physical stability of drugs
Ingår i European Journal of Pharmaceutical Sciences, s. 323-332, 2013.
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DOI för Early drug development predictions of glass-forming ability and physical stability of drugs Ladda ner fulltext (pdf) av Early drug development predictions of glass-forming ability and physical stability of drugs
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Optimizing Solubility and Permeability of a Biopharmaceutics Classification System (BCS) Class 4 Antibiotic Drug Using Lipophilic Fragments Disturbing the Crystal Lattice
Ingår i Journal of Medicinal Chemistry, s. 2690-2694, 2013.
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Computational Prediction of CNS Drug Exposure Based on a Novel In Vivo Dataset
Ingår i Pharmaceutical research, s. 3131-3142, 2012.
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DOI för Computational Prediction of CNS Drug Exposure Based on a Novel In Vivo Dataset
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Ethanol Effects on Apparent Solubility of Poorly Soluble Drugs in Simulated Intestinal Fluid
Ingår i Molecular Pharmaceutics, s. 1942-1952, 2012.
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DOI för Ethanol Effects on Apparent Solubility of Poorly Soluble Drugs in Simulated Intestinal Fluid
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Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors
Ingår i Journal of Pharmaceutical Sciences, s. 3763-3772, 2011.
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Toward In Silico Prediction of Glass-Forming Ability from Molecular Structure Alone: A Screening Tool in Early Drug Development
Ingår i Molecular Pharmaceutics, s. 498-506, 2011.
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Interaction of 140 orally administered drugs with the liver-specific organic anion transporter OATP1B1 (SLCO1B1)
Ingår i Drug metabolism reviews (Softcover ed.), s. 304-305, 2010.
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Dissolution Rate and Apparent Solubility of Poorly Soluble Drugs in Biorelevant Dissolution Media
Ingår i Molecular pharmaceutics, s. 1419-1430, 2010.
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A Modified Physiological BCS for Prediction of Intestinal Absorption in Drug Discovery
Ingår i Molecular pharmaceutics, s. 1478-1487, 2010.
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DOI för A Modified Physiological BCS for Prediction of Intestinal Absorption in Drug Discovery
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Hepatitis C virus NS3 protease inhibitors: large, flexible molecules of peptide origin show satisfactory permeability across Caco-2 cells
Ingår i European Journal of Pharmaceutical Sciences, s. 556-563, 2009.
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Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs
Ingår i Pharmaceutical research, s. 1816-1831, 2009.
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In Vitro and In Silico Strategies to Identify OATP1B1 Inhibitors and Predict Clinical Drug-Drug Interactions
Ingår i Pharmaceutical research, s. 411-426, 2012.
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Computational models to predict aqueous drug solubility, permeability and intestinal absorption
Ingår i Expert opinion on drug metabolism & toxicology, s. 613-627, 2005.
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Theoretical predictions of drug absorption in drug discovery and development
Ingår i Clinical Pharmacokinetics, s. 877-899, 2002.
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Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1
Ingår i Journal of Medicinal Chemistry, s. 5932-5942, 2008.
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Molecular characteristics for solid-state limited solubility
Ingår i Journal of Medicinal Chemistry, s. 3035-3039, 2008.
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DOI för Molecular characteristics for solid-state limited solubility
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Photoinduced Formation of N2 Molecules in Ammonium Compounds
Ingår i Journal of Physical Chemistry A, s. 9662-9669, 2007.
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DOI för Photoinduced Formation of N2 Molecules in Ammonium Compounds
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Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2)
Ingår i Journal of Medicinal Chemistry, s. 3275-3287, 2008.
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A Global Drug Inhibition Pattern for the Human ATP-Binding Cassette Transporter Breast Cancer Resistance Protein (ABCG2)
Ingår i Journal of Pharmacology and Experimental Therapeutics, s. 19-30, 2007.
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Poorly soluble marketed drugs display solvation limited solubility
Ingår i Journal of Medicinal Chemistry, s. 5858-5862, 2007.
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DOI för Poorly soluble marketed drugs display solvation limited solubility
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X-ray yield and selectively excited X-ray emission spectra of atenolol and nadolol.
Ingår i J Electr Spectr, s. 283-285, 2005.
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Contribution of solid-state properties to the aqueous solubility of drugs.
Ingår i Eur J Pharm Sci, s. 294-305, 2006.
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