Alla publikationer från Artursson
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Epithelial and microbial determinants of colonic drug distribution
Ingår i European Journal of Pharmaceutical Sciences, 2023.
DOI för Epithelial and microbial determinants of colonic drug distribution Ladda ner fulltext (pdf) av Epithelial and microbial determinants of colonic drug distribution
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Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis
Ingår i Computational and Structural Biotechnology Journal, s. 4361-4369, 2023.
DOI för Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis Ladda ner fulltext (pdf) av Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis
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Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane
Ingår i Journal of Neuroscience, s. 2222-2241, 2023.
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Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat
Ingår i ACS Nano, 2022.
DOI för Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat Ladda ner fulltext 1 (pdf) av Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat Ladda ner fulltext 2 (pdf) av Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat
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Correlations between 4 beta-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range
Ingår i European Journal of Clinical Pharmacology, s. 1289-1299, 2022.
DOI för Correlations between 4 beta-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range Ladda ner fulltext (pdf) av Correlations between 4 beta-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range
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Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity
Ingår i Clinical Pharmacology and Therapeutics, s. 1142-1154, 2022.
DOI för Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity Ladda ner fulltext (pdf) av Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity
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Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation
Ingår i International Journal of Molecular Sciences, 2022.
DOI för Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation Ladda ner fulltext (pdf) av Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation
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High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3
Ingår i Pharmaceutical research, s. 1599-1613, 2022.
DOI för High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3 Ladda ner fulltext (pdf) av High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3
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Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity
Ingår i Clinical and Translational Science, s. 2685-2696, 2022.
DOI för Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity Ladda ner fulltext (pdf) av Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity
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Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration
Ingår i Biomedicine and Pharmacotherapy, 2022.
DOI för Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration Ladda ner fulltext (pdf) av Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration
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Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ
Ingår i Nucleic Acids Research, s. e129-e129, 2022.
DOI för Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ Ladda ner fulltext (pdf) av Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ
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Professor Margareta Hammarlund-Udenaes - Humbled Scientist Shaping Modern Neuropharmacokinetics
Ingår i Pharmaceutical research, s. 1283-1289, 2022.
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Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity
Ingår i British Journal of Clinical Pharmacology, s. 4121-4133, 2022.
DOI för Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity Ladda ner fulltext (pdf) av Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity
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Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity: a non-randomized three-armed controlled trial
Ingår i Clinical and Translational Science, s. 221-233, 2022.
DOI för Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity: a non-randomized three-armed controlled trial Ladda ner fulltext (pdf) av Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity: a non-randomized three-armed controlled trial
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The impact of inflammation on the expression of drug transporters and metabolic enzymes in colonic tissue from ulcerative colitis patients
Ingår i International Journal of Pharmaceutics, 2022.
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Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis
Ingår i Journal of Experimental & Clinical Cancer Research, 2021.
DOI för Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis Ladda ner fulltext (pdf) av Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis
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Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
Ingår i iScience, 2021.
DOI för Conditions for maintenance of hepatocyte differentiation and function in 3D cultures Ladda ner fulltext (pdf) av Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
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Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
Ingår i Advanced Drug Delivery Reviews, s. 289-331, 2021.
DOI för Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network Ladda ner fulltext (pdf) av Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
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Expanding the Efflux In Vitro Assay Toolbox: A CRISPR-Cas9 Edited MDCK Cell Line with Human BCRP and Completely Lacking Canine MDR1
Ingår i Journal of Pharmaceutical Sciences, s. 388-396, 2021.
DOI för Expanding the Efflux In Vitro Assay Toolbox: A CRISPR-Cas9 Edited MDCK Cell Line with Human BCRP and Completely Lacking Canine MDR1 Ladda ner fulltext (pdf) av Expanding the Efflux In Vitro Assay Toolbox: A CRISPR-Cas9 Edited MDCK Cell Line with Human BCRP and Completely Lacking Canine MDR1
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Getting a grip with kirigami
Ingår i Nature Materials, s. 1043-1044, 2021.
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Hepatocyte size fractionation allows dissection of human liver zonation
Ingår i Journal of Cellular Physiology, s. 5885-5894, 2021.
DOI för Hepatocyte size fractionation allows dissection of human liver zonation Ladda ner fulltext (pdf) av Hepatocyte size fractionation allows dissection of human liver zonation
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Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes
Ingår i Molecular Pharmaceutics, s. 1792-1805, 2021.
DOI för Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes Ladda ner fulltext (pdf) av Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes
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Newly developed dual topoisomerase inhibitor P8-D6 is highly active in ovarian cancer
Ingår i THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 2021.
DOI för Newly developed dual topoisomerase inhibitor P8-D6 is highly active in ovarian cancer Ladda ner fulltext (pdf) av Newly developed dual topoisomerase inhibitor P8-D6 is highly active in ovarian cancer
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Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease
Ingår i Journal of Pharmaceutical Sciences, s. 239-250, 2021.
DOI för Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease Ladda ner fulltext (pdf) av Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease
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Proteomics‐Informed Prediction of Rosuvastatin Plasma Profiles in Patients with a Wide Range of Body Weight
Ingår i Clinical Pharmacology and Therapeutics, s. 762-771, 2021.
DOI för Proteomics‐Informed Prediction of Rosuvastatin Plasma Profiles in Patients with a Wide Range of Body Weight Ladda ner fulltext (pdf) av Proteomics‐Informed Prediction of Rosuvastatin Plasma Profiles in Patients with a Wide Range of Body Weight
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A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity
Ingår i Drug Metabolism And Disposition, s. 8-17, 2020.
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A new opening for orally taken peptide drugs
Ingår i Nature Biomedical Engineering, s. 12-13, 2020.
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Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions
Ingår i Pharmaceutics, 2020.
DOI för Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions Ladda ner fulltext (pdf) av Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions
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Cell-type-resolved proteomic analysis of the human liver
Ingår i Liver international, s. 1770-1780, 2020.
DOI för Cell-type-resolved proteomic analysis of the human liver Ladda ner fulltext (pdf) av Cell-type-resolved proteomic analysis of the human liver
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Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy
Ingår i Nature Communications, 2020.
DOI för Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy Ladda ner fulltext (pdf) av Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy
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Global variability analysis of mRNA and protein concentrations across and within human tissues
Ingår i NAR Genomics and Bioinformatics, 2020.
DOI för Global variability analysis of mRNA and protein concentrations across and within human tissues Ladda ner fulltext (pdf) av Global variability analysis of mRNA and protein concentrations across and within human tissues
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The Critical Role of Passive Permeability in Designing Successful Drugs
Ingår i ChemMedChem, s. 1862-1874, 2020.
DOI för The Critical Role of Passive Permeability in Designing Successful Drugs
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A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (f(u,cell))
Ingår i Pharmaceutical research, 2019.
DOI för A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (f(u,cell)) Ladda ner fulltext (pdf) av A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (f(u,cell))
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A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes
Ingår i Archives of Toxicology, s. 819-829, 2019.
DOI för A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes Ladda ner fulltext (pdf) av A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes
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Comprehensive drug uptake transporter proteomics and metabolomic profiling of human liver
Ingår i Naunyn-Schmiedeberg's Archives of Pharmacology, s. S8-S8, 2019.
DOI för Comprehensive drug uptake transporter proteomics and metabolomic profiling of human liver
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Experimental approaches to understand intracellular based drug bioavailability
Ingår i Drug Metabolism and Pharmacokinetics, s. S3-S3, 2019.
DOI för Experimental approaches to understand intracellular based drug bioavailability
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Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies
Ingår i AAPS Journal, 2019.
DOI för Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies Ladda ner fulltext (pdf) av Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies
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Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations
Ingår i Scientific Reports, 2019.
DOI för Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations Ladda ner fulltext (pdf) av Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations
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Multiple-Enzyme-Digestion Strategy Improves Accuracy and Sensitivity of Label- and Standard-Free Absolute Quantification to a Level That Is Achievable by Analysis with Stable Isotope-Labeled Standard Spiking
Ingår i Journal of Proteome Research, s. 217-224, 2019.
DOI för Multiple-Enzyme-Digestion Strategy Improves Accuracy and Sensitivity of Label- and Standard-Free Absolute Quantification to a Level That Is Achievable by Analysis with Stable Isotope-Labeled Standard Spiking Ladda ner fulltext (pdf) av Multiple-Enzyme-Digestion Strategy Improves Accuracy and Sensitivity of Label- and Standard-Free Absolute Quantification to a Level That Is Achievable by Analysis with Stable Isotope-Labeled Standard Spiking
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Toward a Consensus on Applying Quantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper
Ingår i Clinical Pharmacology and Therapeutics, s. 525-543, 2019.
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Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound
Ingår i Scientific Reports, 2018.
DOI för Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound Ladda ner fulltext (pdf) av Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound
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CRISPR-Cas9: A New Addition to the Drug Metabolism and Disposition Tool Box
Ingår i Drug Metabolism And Disposition, s. 1776-1786, 2018.
DOI för CRISPR-Cas9: A New Addition to the Drug Metabolism and Disposition Tool Box
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Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates
Ingår i Drug Metabolism And Disposition, s. 387-396, 2018.
DOI för Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates Ladda ner fulltext (pdf) av Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates
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Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids
Ingår i Molecular Pharmaceutics, s. 2224-2233, 2018.
DOI för Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids Ladda ner fulltext (pdf) av Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids
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A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.
Ingår i Journal of Pharmaceutical Sciences, s. 2909-2913, 2017.
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Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1
Ingår i Journal of Medicinal Chemistry, s. 2148-2154, 2017.
DOI för Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1
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Intracellular drug bioavailability: a new predictor of system dependent drug disposition
Ingår i Scientific Reports, s. 1-12, 2017.
DOI för Intracellular drug bioavailability: a new predictor of system dependent drug disposition Ladda ner fulltext (pdf) av Intracellular drug bioavailability: a new predictor of system dependent drug disposition
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Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors
Ingår i Journal of Medicinal Chemistry, s. 4279-4292, 2017.
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Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery
Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. E6231-E6239, 2017.
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Professor Yuichi Sugiyama: A Brilliant, Creative, Amicable, Charming, and Humorous Pharmaceutical Scientist
Ingår i Journal of Pharmaceutical Sciences, s. 2188-2194, 2017.
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Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2)
Ingår i European Journal of Pharmaceutical Sciences, s. 70-76, 2017.
DOI för Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2)
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Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes
Ingår i Molecular Pharmaceutics, s. 3142-3151, 2017.
DOI för Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes Ladda ner fulltext (pdf) av Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes
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A Tribute to Ronald T. Borchardt-Teacher, Mentor, Scientist, Colleague, Leader, Friend, and Family Man
Ingår i Journal of Pharmaceutical Sciences, s. 370-385, 2016.
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Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures
Ingår i ACS Chemical Neuroscience, s. 1383-1392, 2016.
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CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
Ingår i Nature Communications, 2016.
DOI för CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil Ladda ner fulltext (pdf) av CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
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Comparative proteome analysis of human liver tissue and isolated hepatocytes: application to predictions of hepatic pitavastatin uptake clearance
Ingår i Drug metabolism reviews (Softcover ed.), s. 96-96, 2016.
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Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9
Ingår i Journal of Pharmaceutical Sciences, s. 1017-1021, 2016.
DOI för Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9
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Development of MS- based immunoassays for Cytochrome P450 and transporter quantification
Ingår i Naunyn-Schmiedeberg's Archives of Pharmacology, s. S47-S47, 2016.
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Direct Measurement of Intracellular Compound Concentration by RapidFire Mass Spectrometry Offers Insights into Cell Permeability
Ingår i Journal of Biomolecular Screening, s. 156-164, 2016.
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Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1
Ingår i Journal of Medicinal Chemistry, s. 1140-1148, 2016.
DOI för Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1
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Global proteome changes in liver tissue 6 weeks after FOLFOX treatment of colorectal cancer liver metastases
Ingår i PROTEOMES, 2016.
DOI för Global proteome changes in liver tissue 6 weeks after FOLFOX treatment of colorectal cancer liver metastases Ladda ner fulltext (pdf) av Global proteome changes in liver tissue 6 weeks after FOLFOX treatment of colorectal cancer liver metastases
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Impact of drug transporters on intracellular unbound drug concentrations
Ingår i Drug metabolism reviews (Softcover ed.), s. 147-147, 2016.
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In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes
Ingår i Journal of Proteomics, s. 234-247, 2016.
DOI för In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes Ladda ner fulltext (pdf) av In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes
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Mechanistic modeling of hepatic pitavastatin disposition: a proteomics-informed bottom-up approach
Ingår i Drug metabolism reviews (Softcover ed.), s. 56-57, 2016.
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Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach
Ingår i Drug Metabolism And Disposition, s. 505-516, 2016.
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New cell-based approaches for better predictions of drug transport and cellular drug exposure
Ingår i Drug metabolism reviews (Softcover ed.), s. 7-7, 2016.
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Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues
Ingår i Advanced Drug Delivery Reviews, s. 256-276, 2016.
DOI för Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues Ladda ner fulltext (pdf) av Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues
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Protein quantification of human hepatic drug transporters and metabolizing enzymes: an inter-laboratory and methodological comparison
Ingår i Drug metabolism reviews (Softcover ed.), s. 98-98, 2016.
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Structural and conformational determinants of macrocycle cell permeability
Ingår i Nature Chemical Biology, s. 1065-+, 2016.
DOI för Structural and conformational determinants of macrocycle cell permeability
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Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions
Ingår i Analytical Biochemistry, s. 82-88, 2016.
DOI för Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions Ladda ner fulltext (pdf) av Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions
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The Need for Speed-Kinetic Limits of Drug Transporters
Ingår i TIPS - Trends in Pharmacological Sciences, s. 243-245, 2016.
DOI för The Need for Speed-Kinetic Limits of Drug Transporters
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The Pro-inflammatory Cytokine Interleukin-6 Regulates Nanoparticle Transport Across Model Follicle-Associated Epithelium Cells
Ingår i Journal of Pharmaceutical Sciences, s. 2099-2104, 2016.
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The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition
Ingår i Journal of Pharmaceutical Sciences, s. 817-827, 2016.
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Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity
Ingår i Journal of Medicinal Chemistry, s. 2094-2108, 2016.
DOI för Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity
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To attach or not to attach: factors behind variable adhesion properties of cryopreserved human hepatocytes
Ingår i Drug metabolism reviews (Softcover ed.), s. 103-103, 2016.
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Addendum to 'Quantifying the impact of transporters on cellular drug permeability'
Ingår i TIPS - Trends in Pharmacological Sciences, s. 559-559, 2015.
DOI för Addendum to 'Quantifying the impact of transporters on cellular drug permeability'
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Breaking the intestinal barrier to deliver drugs
Ingår i Science, s. 716-717, 2015.
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Comparative Proteomic Analysis of Human Liver Tissue and Isolated Hepatocytes with a Focus on Proteins Determining Drug Exposure
Ingår i Journal of Proteome Research, s. 3305-3314, 2015.
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Global Membrane Protein Analysis Of The Human Liver: Application In Predictions Of Atorvastatin Uptake Clearance
Ingår i Drug metabolism reviews (Softcover ed.), s. 245-246, 2015.
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Quantifying the impact of transporters on cellular drug permeability.
Ingår i TIPS - Trends in Pharmacological Sciences, s. 255-262, 2015.
DOI för Quantifying the impact of transporters on cellular drug permeability. Ladda ner fulltext (pdf) av Quantifying the impact of transporters on cellular drug permeability.
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Structure-activity relationships for lipoprotein lipase agonists that lower plasma triglycerides in vivo
Ingår i European Journal of Medicinal Chemistry, s. 191-209, 2015.
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A High-Throughput Cell-Based Method to Predict the Unbound Drug Fraction in the Brain
Ingår i Journal of Medicinal Chemistry, s. 3005-3010, 2014.
DOI för A High-Throughput Cell-Based Method to Predict the Unbound Drug Fraction in the Brain
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Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket
Ingår i Journal of Medicinal Chemistry, s. 1790-1801, 2014.
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Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs
Ingår i European Journal of Pharmaceutical Sciences, s. 173-199, 2014.
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Exploration and pharmacokinetic profiling of phenylalanine based carbamates as novel substance p 1-7 analogues
Ingår i ACS Medicinal Chemistry Letters, s. 1272-1277, 2014.
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Hepatic Uptake of Atorvastatin: Influence of Variability in Transporter Expression on Uptake Clearance and Drug-Drug Interactions
Ingår i Drug Metabolism And Disposition, s. 1210-1218, 2014.
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Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties
Ingår i Journal of Medicinal Chemistry, s. 2746-2754, 2014.
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Novel Peptidomimetic Hepatitis C Virus NS3/4A Protease Inhibitors Spanning the P2–P1′ Region
Ingår i ACS Medicinal Chemistry Letters, s. 249-254, 2014.
DOI för Novel Peptidomimetic Hepatitis C Virus NS3/4A Protease Inhibitors Spanning the P2–P1′ Region
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Passive Lipoidal Diffusion and Carrier-Mediated Cell Uptake Are Both Important Mechanisms of Membrane Permeation in Drug Disposition
Ingår i Molecular Pharmaceutics, s. 1727-1738, 2014.
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Vinylated linear P2 pyrimidinyloxyphenylglycine based inhibitors of the HCV NS3/4A protease and corresponding macrocycles
Ingår i Bioorganic & Medicinal Chemistry, s. 6595-6615, 2014.
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An Integrated in Vitro Model for Simultaneous Assessment of Drug Uptake, Metabolism, and Efflux
Ingår i Molecular Pharmaceutics, s. 3152-3163, 2013.
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Computational Prospecting for Drug-Transporter Interactions
Ingår i Clinical Pharmacology and Therapeutics, s. 30-32, 2013.
DOI för Computational Prospecting for Drug-Transporter Interactions
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Constrained H-Phe-Phe-NH2 Analogues With High Affinity to the Substance P 1-7 Binding Site and With Improved Metabolic Stability and Cell Permeability
Ingår i Journal of Medicinal Chemistry, s. 4953-4965, 2013.
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Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11)
Ingår i Toxicological Sciences, s. 328-343, 2013.
DOI för Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11) Ladda ner fulltext (pdf) av Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11)
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In vitro characterization of interactions with drug transporting proteins
Ingår i Transporters in Drug Development , s. 37-65, 2013.
DOI för In vitro characterization of interactions with drug transporting proteins
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Optimizing Solubility and Permeability of a Biopharmaceutics Classification System (BCS) Class 4 Antibiotic Drug Using Lipophilic Fragments Disturbing the Crystal Lattice
Ingår i Journal of Medicinal Chemistry, s. 2690-2694, 2013.
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Population pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat
Ingår i Journal of Pharmacokinetics and Pharmacodynamics, s. 117-128, 2013.
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Rapid Measurement of Intracellular Unbound Drug Concentrations
Ingår i Molecular Pharmaceutics, s. 2467-2478, 2013.
DOI för Rapid Measurement of Intracellular Unbound Drug Concentrations
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The value of selected in vitro and in silico methods to predict acute oral toxicity in a regulatory context: Results from the European Project ACuteTox
Ingår i Toxicology in Vitro, s. 1357-1376, 2013.
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Caco-2 monolayers in experimental and theoretical predictions of drug transport
Ingår i Advanced Drug Delivery Reviews, s. 280-289, 2012.
DOI för Caco-2 monolayers in experimental and theoretical predictions of drug transport
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Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug - Drug Interactions
Ingår i Journal of Medicinal Chemistry, s. 4740-4763, 2012.
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Evidence-based approach to assess passive diffusion and carrier-mediated drug transport
Ingår i Drug Discovery Today, s. 905-912, 2012.
DOI för Evidence-based approach to assess passive diffusion and carrier-mediated drug transport
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Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1:: predictions of metformin interactions
Ingår i The Pharmacogenomics Journal, s. 400-411, 2011.
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Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors
Ingår i Journal of Pharmaceutical Sciences, s. 3763-3772, 2011.
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A Modified Physiological BCS for Prediction of Intestinal Absorption in Drug Discovery
Ingår i Molecular pharmaceutics, s. 1478-1487, 2010.
DOI för A Modified Physiological BCS for Prediction of Intestinal Absorption in Drug Discovery
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Coexistence of passive and carrier-mediated processes in drug transport
Ingår i Nature reviews. Drug discovery, s. 597-614, 2010.
DOI för Coexistence of passive and carrier-mediated processes in drug transport
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In vitro ADMET and physicochemical investigations of poly-N-methylated peptides designed to inhibit Aβ aggregation
Ingår i Bioorganic & Medicinal Chemistry, s. 5896-5902, 2010.
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Integrated cell models for prediction of drug transport and drug metabolism in the human hepatocyte
Ingår i Drug metabolism reviews (Softcover ed.), s. 306-307, 2010.
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Interaction of 140 orally administered drugs with the liver-specific organic anion transporter OATP1B1 (SLCO1B1)
Ingår i Drug metabolism reviews (Softcover ed.), s. 304-305, 2010.
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Molecular design of chitosan gene delivery systems with an optimized balance between polyplex stability and polyplex unpacking
Ingår i Biomaterials, s. 975-987, 2010.
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Paracellular porosity and pore size of the human intestinal epithelium in tissue and cell culture models
Ingår i Journal of Pharmaceutical Sciences, s. 2166-2175, 2010.
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Specific and general inhibitors of the three hepatic organic anion transporters OATP1B1 (SLCO1B1), OATP1B3 (SLCO1B3) and OATP2B1 (SLCO2B1)
Ingår i Drug metabolism reviews (Softcover ed.), s. 305-306, 2010.
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Uptake mechanism of ochratoxin A and citrinin through human liver
Ingår i Drug metabolism reviews (Softcover ed.), s. 315-315, 2010.
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Endogenous Gene and Protein Expression of Drug Transporting Proteins in Cell Lines Routinely used in Drug Discovery Programs
Ingår i Drug Metabolism And Disposition, s. 2275-2283, 2009.
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Hepatitis C virus NS3 protease inhibitors: large, flexible molecules of peptide origin show satisfactory permeability across Caco-2 cells
Ingår i European Journal of Pharmaceutical Sciences, s. 556-563, 2009.
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Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs
Ingår i Pharmaceutical research, s. 1816-1831, 2009.
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Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories
Ingår i European Journal of Pharmaceutical Sciences, s. 383-396, 2008.
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Molecular characteristics for solid-state limited solubility
Ingår i Journal of Medicinal Chemistry, s. 3035-3039, 2008.
DOI för Molecular characteristics for solid-state limited solubility
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Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2)
Ingår i Journal of Medicinal Chemistry, s. 3275-3287, 2008.
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Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1
Ingår i Journal of Medicinal Chemistry, s. 5932-5942, 2008.
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Tailoring of chitosans for gene delivery: novel self-branched glycosylated chitosan oligomers with improved functional properties
Ingår i Biomacromolecules, s. 3268-76, 2008.
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Yersinia pseudotuberculosis induces transcytosis of nanoparticles across human intestinal villus epithelium via invasin-dependent macropinocytosis
Ingår i Laboratory investigation; a journal of technical methods and pathology, s. 1215-26, 2008.
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A Global Drug Inhibition Pattern for the Human ATP-Binding Cassette Transporter Breast Cancer Resistance Protein (ABCG2)
Ingår i Journal of Pharmacology and Experimental Therapeutics, s. 19-30, 2007.
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Advantages and disadvantages of using bovine serum albumin and/or Cremophor EL as extracellular additives during transport studies of lipophilic compounds across Caco-2 monolayers
Ingår i Journal of drug delivery science and technology, s. 259-266, 2007.
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Beta- and gamma-di- and tripeptides as potential substrates for the oligopeptide transporter hPepT1
Ingår i Journal of Medicinal Chemistry, s. 5238-5242, 2007.
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Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers
Ingår i Nature Protocols, s. 2111-2119, 2007.
DOI för Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers
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Efflux transporters in ulcerative colitis: decreased expression of BCRP (ABCG2) and Pgp (ABCB1)
Ingår i Inflammatory Bowel Diseases, s. 291-297, 2007.
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Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines
Ingår i Drug Metabolism And Disposition, s. 1333-1340, 2007.
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Passive permeability and active transport models for the prediction of oral absorption
Ingår i Comprehensive medicinal chemistry vol 5, s. 259-278, 2007.
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Cell culture absorption models - state of the art
Ingår i Pharmacokinetic profiling in drug research, s. 71-, 2006.
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Characterization of antigen and bacterial transport in the follicle-associated epithelium of human ileum.
Ingår i Lab Invest, s. 504-16, 2006.
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null
Ingår i European Journal of Pharmaceutical Sciences, s. 295-305, 2006.
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Contribution of solid-state properties to the aqueous solubility of drugs.
Ingår i Eur J Pharm Sci, s. 294-305, 2006.
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Gene expression profiles in mouse lung tissue after administration of two cationic polymers used for nonviral gene delivery
Ingår i Pharmaceutical research, s. 475-482, 2006.
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Identification of Cell Adhesion Molecules in the Human Follicle-Associated Epithelium That Improve Nanoparticle Uptake into the Peyer's Patches
Ingår i Journal of Pharmacology and Experimental Therapeutics, s. 632-639, 2006.
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Impact of extracellular protein binding on passive and active drug transport across Caco-2 cells.
Ingår i Pharm Res, s. 350-9, 2006.
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Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells.
Ingår i Drug Metab Dispos, s. 1423-31, 2006.
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Regional levels of drug transporters along the human intestinal tract: Co-expression of ABC and SLC transporters and comparison with Caco-2 cells
Ingår i European Journal of Pharmaceutical Sciences, s. 269-277, 2006.
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null
Ingår i Journal of controlled release, s. 103-112, 2006.
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Targeted gene delivery with trisaccharide-substituted chitosan oligomers in vitro and after lung administration in vivo
Ingår i Journal of Controlled Release, s. 103-112, 2006.
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null
Ingår i Journal of gene medicine, s. 1215-1222, 2005.
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A miniaturized nebulization catheter for improved gene delivery to the mouse lung.
Ingår i J Gene Med, s. 1215-22, 2005.
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Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA pK flux a method.
Ingår i Eur J Pharm Sci, s. 333-49, 2005.
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null
Ingår i Analytical Chemistry, s. 5488-5493, 2005.
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Characterization of Surface-Modified Nanoparticles for in Vivo Biointeraction. A Sedimentation Field Flow Fractionation Study
Ingår i Analytical Chemistry, s. 5488-5493, 2005.
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null
Ingår i Journal of Medicinal Chemistry, s. 604-613, 2005.
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Exploring the role of different drug transport routes in permeability screening.
Ingår i J Med Chem, s. 604-13, 2005.
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Improvement of absorption enhancing effects of n-dodecyl-beta-D-maltopyranoside by its colon-specific delivery using chitosan microspheres.
Ingår i Int J Pharm, s. 127-, 2005.
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null
Ingår i European Journal of Pharmaceutical Sciences, s. 455-465, 2005.
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Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein.
Ingår i Xenobiotica, s. 785-96, 2005.
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Orally active antiviral tripeptide glycyl-prolyl-glycinamide is activated by CD26 (dipeptidyl peptidase IV) before transport across the intestinal epithelium.
Ingår i Antimicrob Agents Chemother, s. 1087-92, 2005.
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pH-Dependent passive and active transport of acidic drugs across Caco-2 cell monolayers
Ingår i European Journal of Pharmaceutical Sciences, s. 211-220, 2005.
DOI för pH-Dependent passive and active transport of acidic drugs across Caco-2 cell monolayers
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Transport of nanoparticles across an in vitro model of the human intestinal follicle associated epithelium.
Ingår i Eur J Pharm Sci, s. 455-65, 2005.
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X-ray yield and selectively excited X-ray emission spectra of atenolol and nadolol.
Ingår i J Electr Spectr, s. 283-285, 2005.
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Absorption Prediction
Ingår i Profiling in Drug Discovery for Lead Selection, 2004.
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Accuracy of calculated pH-dependent aqueous drug solubility.
Ingår i Eur J Pharm Sci, s. 387-98, 2004.
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Association between the number of coadministered P-glycoprotein inhibitors and serum digoxin levels in patients on therapeutic drug monitoring
Ingår i BMC Medicine, s. 2-8, 2004.
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Contribution of the paracellular route to the pH-dependent epithelial permeability to cationic drugs.
Ingår i J Pharm Sci, s. 2972-84, 2004.
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null
Ingår i Journal of Chemical Information and Computer Sciences, s. 1477-1488, 2004.
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Global and local computational models for aqueous solubility prediction of drug-like molecules.
Ingår i J Chem Inf Comput Sci, s. 1477-88, 2004.
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null
Ingår i Gene Therapy, s. 1441-1452, 2004.
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Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers.
Ingår i Gene Ther, s. 1441-52, 2004.
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A new principle for tight junction modulation based on occludin peptides
Ingår i Molecular Pharmacology, s. 1530-1540, 2003.
DOI för A new principle for tight junction modulation based on occludin peptides
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A New Principle for Tight Junction Modulation Based on Occludin Peptides
Ingår i Molecular Pharmacology, s. 1530-1540, 2003.
DOI för A New Principle for Tight Junction Modulation Based on Occludin Peptides
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Absorption classification of oral drugs based on molecular surface properties
Ingår i Journal of Medicinal Chemistry, s. 558-570, 2003.
DOI för Absorption classification of oral drugs based on molecular surface properties
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Absorption classification of oral drugs based on molecular surface properties
Ingår i Journal of Medicinal Chemistry, s. 558-570, 2003.
DOI för Absorption classification of oral drugs based on molecular surface properties
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An improved cell culture model based on 2/4/A1 cell monolayers for studies of intestinal drug transport: characterization of transport routes
Ingår i Pharmaceutical research, s. 373-381, 2003.
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Computational approaches to drug absorption and bioavailability. 17. Intestinal absorption; the role of polar surface area.
Ingår i Drug Bioavailability – Estimation of Solubility, Permeability, Absorption and Bioavailability, s. 341-, 2003.
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null
Ingår i European Journal of Pharmaceutical Sciences, s. 57-65, 2003.
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null
Ingår i European Journal of Pharmaceutical Sciences, s. 57-65, 2003.
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Enantioselective transport and CYP3A4-mediated metabolism of R/S-verapamilin Caco-2 cell monolayers.
Ingår i Eur J Pharm Sci, s. 57-, 2003.
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Genetic variation in the ATP-binding cassette transporter gene ABCG2(BCRP) in a Swedish population
Ingår i European Journal of Pharmaceutical Sciences, s. 359-364, 2003.
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null
Ingår i Journal of Chemical Information and Computer Sciences, s. 1177-1185, 2003.
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Molecular Descriptors Influencing Melting Point and Their Role in Classification of Solid Drugs.
Ingår i J Chem Inf Comput Sci, s. 1177-, 2003.
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null
Ingår i Gene Therapy, s. 1575-83, 2003.
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PEI - a potent, but not harmless, mucosal immuno-stimulator of mixed T-helper cell response and FasL-mediated cell death in mice
Ingår i Gene Ther, s. 1575-, 2003.
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null
Ingår i Pharmaceutical Research, s. 1141-1148, 2003.
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pH-dependent bidirectional transport of weakly basic drugs across Caco-2monolayers: implications for drug-drug interactions.
Ingår i Pharm Res, s. 1141-, 2003.
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null
Ingår i Pharmaceutical Research, s. 397-405, 2003.
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Prediction of the oral absorption of low-permeability drugs using small intestine-like 2/4/A1 cell monolayers.
Ingår i Pharm Res, s. 397-, 2003.
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null
Ingår i The Journal of Gene Medicine, s. 130-141, 2003.
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Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo.
Ingår i J Gene Med, s. 130-, 2003.
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Studies of membrane permeability and oral absorption 6: Caco-2 and emerging alternatives for prediction of intestinal drug transport: A general overview.
Ingår i Drug Bioavailability - Estimation of Solubility, Permeability, Absorption and Bioavailability, s. 72-, 2003.
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A novel approach for prediction of intestinal absorption of drugs in humans based on hydrogen bond descriptors and structural similarity
Ingår i Quant. Struct.- Act. Relat., s. 402-, 2002.
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Applications of epithelial cell culture in studies of drug transport.
Ingår i Methods Mol Biol, s. 233-, 2002.
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Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues
Ingår i European Journal of Pharmaceutical Sciences, s. 113-118, 2002.
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null
Ingår i Pharmaceutical Research, s. 182-188, 2002.
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Experimental and computational screening models for prediction of aqueous drug solubility.
Ingår i Pharm Res, s. 182-, 2002.
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Preparation and characterization of chitosans with oligosaccharide branches
Ingår i Carbohydr Res, s. 2455-, 2002.
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Tetanus antigen modulates the gene expression profile of aluminium phosphate adjuvant in spleen lymphocytes in vivo.
Ingår i Pharmacogenomics J, s. 57-, 2002.
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null
Ingår i The Pharmacogenomics Journal, s. 57-64, 2002.
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null
Ingår i The Pharmacogenomics Journal, s. 57-64, 2002.
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Theoretical predictions of drug absorption in drug discovery and development.
Ingår i Clin Pharmacokinet, s. 877-, 2002.
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Theoretical predictions of drug absorption in drug discovery and development
Ingår i Clinical Pharmacokinetics, s. 877-899, 2002.
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Caco-2 monolayers in experimental and theoretical predictions of drugtransport.
Ingår i Adv. Drug Deliv. Rev., s. 27-, 2001.
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Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and inhuman intestinal epithelial Caco-2 cell monolayers
Ingår i Journal of Pharmacology and Experimental Therapeutics, s. 164-170, 2001.
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null
Ingår i Journal of Pharmaceutical Sciences, s. 1736-1751, 2001.
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CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell linessuitable for drug transport studies.
Ingår i J Pharm Sci, s. 1736-, 2001.
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Experimental and computational screening models for the prediction of intestinal drug absorption.
Ingår i J Med Chem, s. 1927-, 2001.
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Transport of lipophilic drug molecules in a new mucus-secreting cellculture model based on HT29-MTX cells.
Ingår i Pharm Res, s. 1138-, 2001.
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A new method for preparing biodegradable microparticles and entrapment of hydrocortisone in DL-PLG microparticles using supercritical fluids
Ingår i Eur. J. Pharm. Sci., s. 1-, 2000.
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null
Ingår i Biochemical Biophysical Research Communications, s. 808-813, 2000.
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Expression of specific markers and particle transport in a new humanintestinal M-cell model.
Ingår i Biochem Biophys Res Commun, s. 808-, 2000.
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Virtual screening of intestinal drug permeability
Ingår i J CONTROLLED RELEASE, s. 231-, 2000.
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A conditionally immortalized epithelial cell line for studies of intestinal drug transport
Ingår i J PHARMACO EXP THERAPEUTICS, s. 1212-, 1999.
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Chitosans as absorption enhancers of poorly absorbable drugs 3: Influence of mucus on absorption enhancement
Ingår i Eur J Pharm Sci, s. 335-, 1999.
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null
Ingår i Journal of Pharmacology and Experimental Therapeutics, s. 1212–1221-, 1999.
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Conditionally immortalized rat fetal epithelial cell line (2/4/A1): A new model for studying apoptosis in the gut?
Ingår i Gastroenterology, s. 3949-, 1999.
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Effect of molecular charge on intestinal epithelial drug transport: pH-dependent transport of cationic drugs
Ingår i J PHARMACO EXP THERAPEUTICS, s. 435-, 1999.
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Encapsulation of rotavirus into poly(lactide-co-glycolide) microspheres
Ingår i J Controlled Release, s. 377-, 1999.
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Encapsulation of rotavirus into poly(lactide-co-glydolide) microspheres
Ingår i Journal of Controlled Release, s. 377-389, 1999.
DOI för Encapsulation of rotavirus into poly(lactide-co-glydolide) microspheres
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Novel lipoamino acid- and liposaccharide-based system for peptide delivery: Application for oral administration of tumor-selective somatostatin analogues
Ingår i Journal of Medicinal Chemistry, s. 4010-1013, 1999.
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Paracellular drug transport across intestinal epithelia: influence of charge and induced water flux
Ingår i Eur J Pharm Sci, s. 47-, 1999.
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Prediction of membrane permeability to peptides from calculated dynamic molecular surface properties.
Ingår i Pharm Res, s. 205-, 1999.
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Prediction of the intestinal absorption of endothelin receptor antagonistsusing three theoretical methods of increasing complexity.
Ingår i Pharm Res, s. 1520-, 1999.
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Preparation of biodegradable microparticles using solution-enhanced dispersion by supercritical fluids (SEDS)
Ingår i Pharm Res, s. 676-, 1999.
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Theoretical calculation and prediction of intestinal absorption of drugs in humans using MolSurf parametrization and PLS statistics
Ingår i Eur J Pharm Sci, s. 49-, 1999.
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Absorption enhancement in intestinal epithelial Caco-2 monolayers by sodium caprate: Assessment of molecular weight dependence and demonstration of transport routes
Ingår i Journal of drug targeting (Print), s. 215-223, 1998.
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Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells
Ingår i J PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, s. 362-, 1998.
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Conditionally immortalized intestinal epithelial cells - A new model for studying intestinal epithelial cell turnover
Ingår i Ann.NY Acad.Sci., s. 201-, 1998.
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Evaluation of dynamic polar molecular surface area as predictor of drug absorption: Comparison with other computational and experimental predictors
Ingår i J MEDI CHEM, s. 5382-, 1998.
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Integrity and metabolism of human ileal mucosa in vitro in the Ussing chamber
Ingår i Acta Physiol. Scand., s. 47-, 1998.
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The influence of intestinal mucus components on the diffusion of drugs
Ingår i PHARMACEUTICAL RESEARCH, s. 66-, 1998.
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Comparison of CYP3A activities in a subclone of Caco-2 cells (TC7) and human intestine
Ingår i PHARMACEUTICAL RESEARCH, s. 1019-, 1997.
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Diffusion of drugs in native and purified gastrointestinal mucus
Ingår i JOURNAL OF PHARMACEUTICAL SCIENCES, s. 660-, 1997.
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Experimental and theoretical predictions of intestinal drug absorption, in Computer-assisted lead finding and optimization
Ingår i Verlag Helvetica Clinica Acta, 1997.
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Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond
Ingår i PHARMACEUTICAL RESEARCH, s. 1655-, 1997.
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Mechanism of absorption enhancement in humans after rectal administration of ampicillin in suppositories containing sodium caprate
Ingår i PHARMACEUTICAL RESEARCH, s. 930-, 1997.
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Polar molecular surface properties predict the intestinal absorption of drugs in humans
Ingår i PHARMACEUTICAL RESEARCH, s. 568-, 1997.
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Theoretical calculation and prediction of Caco-2 cell permeability using MolSurf parametrization and PLS statistics
Ingår i PHARMACEUTICAL RESEARCH, s. 1786-, 1997.
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Cell cultures to assess drug transport and metabolism - Preface
Ingår i ADVANCED DRUG DELIVERY REVIEWS, s. 1-, 1996.
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Chitosans as absorption enhancers for poorly absorbable drugs .1. Influence of molecular weight and degree of acetylation on drug transport across human intestinal epithelial (Caco-2) cells
Ingår i PHARMACEUTICAL RESEARCH, s. 1686-, 1996.
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Comparison between active and passive drug transport in human intestinal epithelial (Caco-2) cells in vitro and human jejunum in vivo
Ingår i INTERNATIONAL JOURNAL OF PHARMACEUTICS, s. 103-, 1996.
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Correlation of drug absorption with molecular surface properties
Ingår i JOURNAL OF PHARMACEUTICAL SCIENCES, s. 32-, 1996.
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Oral absorption studies of lipid-polylysine conjugates of thyrotropin releasing hormone (TRH) and luteinizing hormone releasing hormone (LHRH)
Ingår i INTERNATIONAL JOURNAL OF PHARMACEUTICS, s. 167-, 1996.
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Permeability of 5-fluorouracil and prodrugs in Caco-2 cell monolayers.
Ingår i INTERNATIONAL JOURNAL OF PHARMACEUTICS, s. 223-, 1996.
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Studying transport in absorptive epithelia
Ingår i Cell models of epithelial tissues - A practical approach, s. 111-, 1996.
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Transport of an influenza virus vaccine formulation (iscom) in Caco-2 cells
Ingår i American Journal of Physiology, s. G554-G564, 1996.
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COCULTURES OF HUMAN INTESTINAL GOBLET (HT29-H) AND ABSORPTIVE (CACO-2) CELLS FOR STUDIES OF DRUG AND PEPTIDE ABSORPTION
Ingår i EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, s. 171-, 1995.
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MECHANISMS OF ABSORPTION ENHANCEMENT BY MEDIUM-CHAIN FATTY-ACIDS IN INTESTINAL EPITHELIAL CACO-2 CELL MONOLAYERS
Ingår i JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, s. 958-, 1995.
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STARCH MICROSPHERES INDUCE PULSATILE DELIVERY OF DRUGS AND PEPTIDES ACROSS THE EPITHELIAL BARRIER BY REVERSIBLE SEPARATION OF THE TIGHT JUNCTIONS
Ingår i JOURNAL OF DRUG TARGETING, s. 501-, 1995.
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Microspheres as drug carriers
some consequences of the delivery of microparticles to the reticuloendothelial system Artursson, Per
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null
Ingår i Gene Therapy