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Half-time seminar: Influence of intra- and extracellular free drug concentrations in the human colon on local and systemic drug exposure
Rebekkah Hammar, Phd Student at the Department of Pharmacy and SweDeliver, presents her work to determine drug distribution in human colonoids and microbiota models to create a PBPK model of the colonic environment. Thus, enabling better estimation of colonic drug efficacy and to reduce the need for animal models.